Literature DB >> 6842590

Complementary DNA sequence of a human cytoplasmic actin. Interspecies divergence of 3' non-coding regions.

I Hanukoglu, N Tanese, E Fuchs.   

Abstract

We have isolated and sequenced a cloned complementary DNA insert complementary to the messenger RNA of a cytoplasmic actin expressed in human epidermal cells. This provides the first cytoplasmic actin complementary DNA sequence for a vertebrate organism. The actin amino acid sequence predicted from this complementary DNA is identical to that of a bovine cytoplasmic actin and shows 98 and 85% homology with a Dictyostelium and a yeast actin, respectively. The complementary DNA sequence indicates that the 3' end of the mRNA contains an unusually long (greater than 400 nucleotides) 3' non-translated region. A comparison of this 3' non-coding region with those of recently determined actin complementary DNA sequences from other species reveals little or no homology among these sequences. Thus, these results indicate that although the actin amino acid sequences are extremely conserved, the non-coding regions of the mRNAs diverge rapidly.

Entities:  

Mesh：

Substances：

Year:  1983        PMID： 6842590     DOI： 10.1016/0022-2836(83)90117-1

Source DB:  PubMed          Journal:  J Mol Biol        ISSN： 0022-2836            Impact factor:   5.469


  39 in total

1.  Role of regulatory elements and the MAPK/ERK or p38 MAPK pathways for activation of human cytomegalovirus gene expression.

Authors:  Jiping Chen; Mark F Stinski
Journal:  J Virol       Date:  2002-05       Impact factor: 5.103

2.  Consistent transcription of the Epstein-Barr virus LMP2 gene in nasopharyngeal carcinoma.

Authors:  P Busson; R McCoy; R Sadler; K Gilligan; T Tursz; N Raab-Traub
Journal:  J Virol       Date:  1992-05       Impact factor: 5.103

3.  Characterization of the testes-specific pim-1 transcript in rat.

Authors:  D Wingett; R Reeves; N S Magnuson
Journal:  Nucleic Acids Res       Date:  1992-06-25       Impact factor: 16.971

4.  Characterization of the linker 2 region in human vimentin using site-directed spin labeling and electron paramagnetic resonance.

Authors:  John F Hess; Madhu S Budamagunta; Rebecca L Shipman; Paul G FitzGerald; John C Voss
Journal:  Biochemistry       Date:  2006-10-03       Impact factor: 3.162

5.  MCL1, a gene expressed in programmed myeloid cell differentiation, has sequence similarity to BCL2.

Authors:  K M Kozopas; T Yang; H L Buchan; P Zhou; R W Craig
Journal:  Proc Natl Acad Sci U S A       Date:  1993-04-15       Impact factor: 11.205

6.  Senescent cells fail to express cdc2, cycA, and cycB in response to mitogen stimulation.

Authors:  G H Stein; L F Drullinger; R S Robetorye; O M Pereira-Smith; J R Smith
Journal:  Proc Natl Acad Sci U S A       Date:  1991-12-15       Impact factor: 11.205

7.  Herpes simplex virus-infected cells contain a function(s) that destabilizes both host and viral mRNAs.

Authors:  A D Kwong; N Frenkel
Journal:  Proc Natl Acad Sci U S A       Date:  1987-04       Impact factor: 11.205

8.  Effects of herpes simplex virus on mRNA stability.

Authors:  T Strom; N Frenkel
Journal:  J Virol       Date:  1987-07       Impact factor: 5.103

9.  The protection of novel 2-arylethenylquinoline derivatives against impairment of associative learning memory induced by neural Aβ in C. elegans Alzheimer's disease model.

Authors:  Qidi He; Guan Huang; Yixin Chen; Xiaoqin Wang; Zhishu Huang; Zuanguang Chen
Journal:  Neurochem Res       Date:  2017-07-01       Impact factor: 3.996

10.  Cloning of the gamma-aminobutyric acid (GABA) rho 1 cDNA: a GABA receptor subunit highly expressed in the retina.

Authors:  G R Cutting; L Lu; B F O'Hara; L M Kasch; C Montrose-Rafizadeh; D M Donovan; S Shimada; S E Antonarakis; W B Guggino; G R Uhl
Journal:  Proc Natl Acad Sci U S A       Date:  1991-04-01       Impact factor: 11.205
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.