Literature DB >> 6841650

Comparison of the effects of filtration leucapheresis and discontinuous flow centrifugation leucapheresis on granulocyte microbicidal function.

S Martin, A T Ghoneim, E A Robinson, J A Child.   

Abstract

In an investigation of the in vitro phagocytic and microbicidal function of granulocytes collected by filtration leucapheresis (FL) from 18 donors and by discontinuous flow centrifugation leucapheresis (DFC) from six donors, comparison was made with the function of granulocytes obtained from the same donors by venepuncture and density gradient centrifugation over Ficoll-Isopaque (FI). No significant impairment of the phagocytosis or killing of Candida guilliermondii by either FL- or DFC-granulocytes was observed. Although the ability of FL-granulocytes to phagocytose and kill Staphylococcus aureus did not differ significantly from the function of control FI-granulocytes, DFC-granulocytes were significantly less active.

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Mesh：

Year:  1983        PMID： 6841650      PMCID： PMC498292          DOI： 10.1136/jcp.36.5.586

Source DB:  PubMed          Journal:  J Clin Pathol        ISSN： 0021-9746            Impact factor:   3.411


  19 in total

1.  Granulocyte bactericidal capacity and chemotaxis as affected by continuous-flow centrifugation and filtration leukapheresis, steroid administration, and storage.

Authors:  R T Steigbigel; J Baum; J L MacPherson; J Nusbacher
Journal:  Blood       Date:  1978-07       Impact factor: 22.113

2.  In vitro function and post-transfusion survival of granulocytes collected by continuous-flow centrifugation and by filtration leukapheresis.

Authors:  J McCullough; B J Weiblen; A R Deinard; J Boen; I E Fortuny; P G Quie
Journal:  Blood       Date:  1976-08       Impact factor: 22.113

3.  Influence of phenylbutazone on the phagocytic and bactericidal activities of neutrophil granulocytes.

Authors:  C O Solberg
Journal:  Acta Pathol Microbiol Scand B Microbiol Immunol       Date:  1974-04

Review 4.  Granulocyte transfusion therapy for life-threatening bacteremia: results of transfusion trials at the National Cancer Institute.

Authors:  R G Graw; F G Stout; R H Herzig; G P Herzig
Journal:  Prog Clin Biol Res       Date:  1977

5.  In vitro function of granulocytes isolated from blood of normal volunteers using continuous-flow centrifugation in the IBM-aminco celltrifuge and adhesion-filtration leukapheresis using nylon fiber.

Authors:  P H Wade; E M Skrabut; L Vinciguerra; C R Valeri
Journal:  Transfusion       Date:  1977 Mar-Apr       Impact factor: 3.157

6.  Kinetics of staphylococcal opsonization, attachment, ingestion and killing by human polymorphonuclear leukocytes: a quantitative assay using [3H]thymidine labeled bacteria.

Authors:  J Verhoef; P K Peterson; P G Quie
Journal:  J Immunol Methods       Date:  1977       Impact factor: 2.303

7.  Granulocyte transfusions: evaluation of factors influencing results and a comparison of filtration and intermittent centrifugation leukapheresis.

Authors:  J Aisner; C A Schiffer; P H Wiernik
Journal:  Br J Haematol       Date:  1978-01       Impact factor: 6.998

8.  Comparative morphology of granulocytes collected by three methods of leukapheresis. A light microscopy and transmission electron microscopy study.

Authors:  E Feliu; S Woessner; E Matutes; F Cardellach; A Grañena; P Marin; L Puig; J L Vives-Corrons; E Montserrat; C Rozman
Journal:  Transfusion       Date:  1981 Sep-Oct       Impact factor: 3.157

9.  Phagocytosis measured as inhibition of uridine uptake by Candida albicans.

Authors:  M Yamamura; J Boler; H Valdimarsson
Journal:  J Immunol Methods       Date:  1977       Impact factor: 2.303

10.  Successful granulocyte transfusion therapy for gram-negative septicemia. A prospectively randomized controlled study.

Authors:  R H Herzig; G P Herzig; R G Graw; M I Bull; K K Ray
Journal:  N Engl J Med       Date:  1977-03-31       Impact factor: 91.245
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