Literature DB >> 6840800

Dengue virus-induced cytotoxic factor induces macrophages to produce a cytotoxin.

L Gulati, U C Chaturvedi, A Mathur.   

Abstract

In our earlier studies we have observed that T lymphocytes of dengue type 2 virus (DV)-infected mouse spleen produce a cytotoxic factor (CF). In the present study it has been observed that CF induces mouse spleen and peritoneal macrophages to produce a cytotoxin (CF2) as has been revealed by DEAE-cellulose chromatography. CF2 is produced by an induction process and is present intracellularly as well as leaking out of the cells. CF2 kills most of the macrophages and some of the T cells, as observed with CF. It appears that CF2 is produced to amplify the effect of CF and/or for cooperative action with CF.

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Year:  1983        PMID： 6840800      PMCID： PMC1454098     

Source DB:  PubMed          Journal:  Immunology        ISSN： 0019-2805            Impact factor:   7.397


  20 in total

1.  Dengue virus-induced thymus-derived suppressor cells in the spleen of mice.

Authors:  P Tandon; U C Chaturvedi; A Mathur
Journal:  Immunology       Date:  1979-12       Impact factor: 7.397

2.  Host defence mechanisms against dengue virus infection of mice.

Authors:  U C Chaturvedi; P Tandon; A Mathur; A Kumar
Journal:  J Gen Virol       Date:  1978-05       Impact factor: 3.891

3.  Control of in vitro and in vivo spread of coxsackievirus B4 infection by sensitized spleen cells and antibody.

Authors:  U C Chaturvedi; H O Tandon; A Mathur
Journal:  J Infect Dis       Date:  1978-08       Impact factor: 5.226

4.  A rapid method for the isolation of functional thymus-derived murine lymphocytes.

Authors:  M H Julius; E Simpson; L A Herzenberg
Journal:  Eur J Immunol       Date:  1973-10       Impact factor: 5.532

5.  Effect of immunosuppression on dengue virus infection in mice.

Authors:  U C Chaturvedi; P Tandon; A Mathur
Journal:  J Gen Virol       Date:  1977-09       Impact factor: 3.891

6.  Transmission of dengue virus-induced suppressor signal from macrophage to lymphocyte occurs by cell contact.

Authors:  M I Shukla; U C Chaturvedi
Journal:  Br J Exp Pathol       Date:  1983-02

7.  Macrophage Ia antigens. I. macrophage populations differ in their expression of Ia antigens.

Authors:  C Cowing; B D Schwartz; H B Dickler
Journal:  J Immunol       Date:  1978-02       Impact factor: 5.422

8.  Biochemical study of certain enzymes and metabolites of the carbohydrate metabolism in the skeletal muscle of the dengue virus-infected mice.

Authors:  D K Agrawal; P Tandon; U C Chaturvedi; A Kumar
Journal:  J Gen Virol       Date:  1978-08       Impact factor: 3.891

9.  Production of cytotoxic factor in the spleen of dengue virus-infected mice.

Authors:  U C Chaturvedi; A Bhargava; A Mathur
Journal:  Immunology       Date:  1980-08       Impact factor: 7.397

10.  Characterization of the cytotoxic factor produced in the spleen of dengue virus-infected mice.

Authors:  U C Chaturvedi; H Dalakoti; A Mathur
Journal:  Immunology       Date:  1980-10       Impact factor: 7.397
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  4 in total

1.  Increased capillary permeability mediated by a dengue virus-induced lymphokine.

Authors:  M Khanna; U C Chaturvedi; M C Sharma; V C Pandey; A Mathur
Journal:  Immunology       Date:  1990-03       Impact factor: 7.397

2.  Variable effects of dengue virus-induced cytotoxic factors on different subpopulations of macrophages.

Authors:  U C Chaturvedi; R Nagar; L Gulati; A Mathur
Journal:  Immunology       Date:  1987-07       Impact factor: 7.397

Review 3.  Dengue in India.

Authors:  Nivedita Gupta; Sakshi Srivastava; Amita Jain; Umesh C Chaturvedi
Journal:  Indian J Med Res       Date:  2012-09       Impact factor: 2.375

Review 4.  Pathogenesis of viral infections.

Authors:  L N Potgieter
Journal:  Vet Clin North Am Small Anim Pract       Date:  1986-11       Impact factor: 2.093
  4 in total

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