Literature DB >> 6840430

Concentration-dependent differential effect of retinoic acid on intercellular metabolic cooperation.

T Shuin, R Nishimura, K Noda, M Umeda, T Ono.   

Abstract

A vitamin A analog, 13-cis-retinoic acid (13-cis-RA), was tested for effect on intercellular metabolic cooperation between 6-thioguanine-resistant and -sensitive V79 Chinese hamster cells. Most typical tumor promoters have been reported to inhibit metabolic cooperation. 13-cis-RA was found to enhance metabolic cooperation of cells treated with a potent tumor promoter, 12-O-tetradecanoyl-phorbol-13-acetate. However, inhibition of metabolic cooperation was noticed when 13-cis-RA was used at higher concentrations.

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Year:  1983        PMID: 6840430

Source DB:  PubMed          Journal:  Gan        ISSN: 0016-450X


  3 in total

Review 1.  Human adult stem cells as the target cells for the initiation of carcinogenesis and for the generation of "cancer stem cells".

Authors:  James E Trosko
Journal:  Int J Stem Cells       Date:  2008-11       Impact factor: 2.500

2.  The effect of tumor promoters and antagonists on in vitro directional migration of 10T1/2 mouse embryo cells.

Authors:  H Verschueren
Journal:  Cell Biol Toxicol       Date:  1985-06       Impact factor: 6.691

3.  Differential dose-dependent effects of alpha-, beta-carotenes and lycopene on gap-junctional intercellular communication in rat liver in vivo.

Authors:  V Krutovskikh; M Asamoto; N Takasuka; M Murakoshi; H Nishino; H Tsuda
Journal:  Jpn J Cancer Res       Date:  1997-12
  3 in total

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