Literature DB >> 6840281

Streptozotocin diabetes results in increased responsiveness of adipocyte lipolysis to glucagon.

K Chatzipanteli, D Saggerson.   

Abstract

Adipocytes from streptozotocin-diabetic rats are approximately 50-times more sensitive to the lipolytic action of glucagon. This change is only perceived in the presence of a small quantity of adenosine deaminase which itself has little effect on basal lipolysis. Insulin treatment restores glucagon sensitivity to normal.

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Year:  1983        PMID： 6840281     DOI： 10.1016/0014-5793(83)80225-7

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  5 in total

1.  Enzymes involved in adenosine metabolism in rat white and brown adipocytes. Effects of streptozotocin-diabetes, hypothyroidism, age and sex differences.

Authors:  Z Jamal; E D Saggerson
Journal:  Biochem J       Date:  1987-08-01       Impact factor: 3.857

2.  Sensitivity of adipocyte lipolysis to stimulatory and inhibitory agonists in hypothyroidism and starvation.

Authors:  E D Saggerson
Journal:  Biochem J       Date:  1986-09-01       Impact factor: 3.857

3.  Adipose-tissue Mg2+-dependent phosphatidate phosphohydrolase. Control of activity and subcellular distribution in vitro and in vivo.

Authors:  S J Taylor; E D Saggerson
Journal:  Biochem J       Date:  1986-10-15       Impact factor: 3.857

4.  Hormonal control of substrate cycling in humans.

Authors:  H Miyoshi; G I Shulman; E J Peters; M H Wolfe; D Elahi; R R Wolfe
Journal:  J Clin Invest       Date:  1988-05       Impact factor: 14.808

5.  Changes in the anti-lipolytic action and binding to plasma membranes of N6-L-phenylisopropyladenosine in adipocytes from starved and hypothyroid rats.

Authors:  P Chohan; C Carpenter; E D Saggerson
Journal:  Biochem J       Date:  1984-10-01       Impact factor: 3.857
  5 in total

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