Literature DB >> 6840271

An essential role of cytosolic thioltransferase in protection of pyruvate kinase from rabbit liver against oxidative inactivation.

K Axelsson, B Mannervik.   

Abstract

Pyruvate kinase from rabbit liver is inactivated spontaneously in the presence of air. Glutathione in physiological concentrations gives partial protection against inactivation. Full protection is obtained with glutathione and purified cytosolic thioltransferase supplemented with a glutathione-regenerating system. It is suggested that thioltransferase plus glutathione serve a general function in protecting protein thiol groups against oxidation.

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Year:  1983        PMID： 6840271     DOI： 10.1016/0014-5793(83)80494-3

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  8 in total

1.  Glutaredoxin 2 (Grx2) gene deletion induces early onset of age-dependent cataracts in mice.

Authors:  Hongli Wu; Yibo Yu; Larry David; Ye-Shih Ho; Marjorie F Lou
Journal:  J Biol Chem       Date:  2014-11-01       Impact factor: 5.157

2.  Identification and characterization of three novel cold acclimation-responsive genes from the extremophile hair grass Deschampsia antarctica Desv.

Authors:  Manuel Gidekel; Luis Destefano-Beltrán; Patricia García; Lorena Mujica; Pamela Leal; Marely Cuba; Lida Fuentes; León A Bravo; Luis J Corcuera; Miren Alberdi; Ilona Concha; Ana Gutiérrez
Journal:  Extremophiles       Date:  2003-09-02       Impact factor: 2.395

3.  Involvement of thiol transferase- and thioredoxin-dependent systems in the protection of 'essential' thiol groups of ornithine decarboxylase.

Authors:  F Flamigni; S Marmiroli; C M Caldarera; C Guarnieri
Journal:  Biochem J       Date:  1989-04-01       Impact factor: 3.857

4.  Modeling the activity of glutathione as a hydroxyl radical scavenger considering its neutral non-zwitterionic form.

Authors:  Amarjeet Yadav; Phool C Mishra
Journal:  J Mol Model       Date:  2012-10-10       Impact factor: 1.810

5.  Inhibition of glycolysis in the retina by oxidative stress: prevention by pyruvate.

Authors:  K R Hegde; S Kovtun; Shambhu D Varma
Journal:  Mol Cell Biochem       Date:  2010-06-18       Impact factor: 3.396

6.  Rapid determination of cysteine and chiral discrimination of D-/L-cysteine via the aggregation-induced emission enhancement of gold nanoclusters by Ag.

Authors:  Shengli Ruan; Yan Zhou; Min Zhang; Hongyang Zhang; Yuerong Wang; Ping Hu
Journal:  Anal Sci       Date:  2022-04-01       Impact factor: 2.081

7.  Effects of Terminalia arjuna bark extract on apoptosis of human hepatoma cell line HepG2.

Authors:  Sarveswaran Sivalokanathan; Marati Radhakrishnan Vijayababu; Maruthaiveeran Periyasamy Balasubramanian
Journal:  World J Gastroenterol       Date:  2006-02-21       Impact factor: 5.742

Review 8.  Protein S-glutathionylation reactions as a global inhibitor of cell metabolism for the desensitization of hydrogen peroxide signals.

Authors:  Ryan J Mailloux
Journal:  Redox Biol       Date:  2020-03-07       Impact factor: 11.799
  8 in total

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