Literature DB >> 6840196

Effects of adenosine on [3H]norepinephrine release from perfused mesenteric arteries of SHR and renal hypertensive rats.

T Kubo, C Su.   

Abstract

Adenosine (10-30 microM) inhibited the 3H-efflux evoked by sympathetic nerve stimulation in the perfused rat mesenteric arteries preincubated with [3H]norepinephrine. The inhibition was smaller in the prehypertensive (5 weeks old) as well as hypertensive (15-18 weeks) SHR (spontaneously hypertensive rats), compared with age-matched normotensive Wistar Kyoto rats. However, it was not diminished in Wistar rats rendered hypertensive by left renal artery occlusion. Thus, a diminished adenosine-mediated presynaptic inhibition of adrenergic transmission appears to be genetically inherent in SHR.

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Year:  1983        PMID： 6840196     DOI： 10.1016/0014-2999(83)90352-7

Source DB:  PubMed          Journal:  Eur J Pharmacol        ISSN： 0014-2999            Impact factor:   4.432


  6 in total

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Journal:  Proc Natl Acad Sci U S A       Date:  1988-06       Impact factor: 11.205

Review 2.  Autonomic neuromuscular junctions: current developments and future directions.

Authors:  G Burnstock
Journal:  J Anat       Date:  1986-06       Impact factor: 2.610

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Authors:  G Burnstock; R Crowe; C Kennedy; J Török
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Journal:  Br J Pharmacol       Date:  1995-09       Impact factor: 8.739

5.  Reduced Noradrenergic Signaling in the Spleen Capsule in the Absence of CB1 and CB2 Cannabinoid Receptors.

Authors:  Tyrell J Simkins; David Fried; Kevin Parikh; James J Galligan; John L Goudreau; Keith J Lookingland; Barbara L F Kaplan
Journal:  J Neuroimmune Pharmacol       Date:  2016-06-10       Impact factor: 4.147

6.  Hemodynamic and neurohumoral effects of various grades of selective adenosine transport inhibition in humans. Implications for its future role in cardioprotection.

Authors:  G A Rongen; P Smits; K Ver Donck; J J Willemsen; R A De Abreu; H Van Belle; T Thien
Journal:  J Clin Invest       Date:  1995-02       Impact factor: 14.808
  6 in total

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