Literature DB >> 6840166

A naturalistic study of hypertension in a rural U.K. community. 2 Years results.

P J Fell, J M Shakespeare, N P Watson, H F O'Donnell.   

Abstract

A naturalistic study was set up to screen, identify and treat hypertensive patients aged 20-60 years in a rural general practice. 3,222 patients (92%) of a stable population of 3,489 were screened by 2 nurse research assistants and of these 455 patients (14%) were found to be hypertensive or borderline hypertensive. After careful assessment, 192 of these patients were found suitable for treatment and subsequently 138 entered the study. Two well recognised treatment regimes were used and no significant difference between patient response resulted. 84 patients (60.9%) completed the 2 year duration of the study discussed here. The cost of the study is not feasible in an average general practice, but day to day running of such a project, run along clearly defined treatment regimes was managed easily by 2 research assistants: this reduced, therefore, the work load on individual general practitioners.

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Year:  1983        PMID: 6840166     DOI: 10.1007/bf00613816

Source DB:  PubMed          Journal:  Eur J Clin Pharmacol        ISSN: 0031-6970            Impact factor:   2.953


  12 in total

1.  Hemodynamic and hypotensive effects of long-term therapy with chlorothiazide.

Authors:  J CONWAY; P LAUWERS
Journal:  Circulation       Date:  1960-01       Impact factor: 29.690

2.  Blood-pressure screening and supervision in general practice.

Authors:  J H Barber; D G Beevers; R Fife; V M Hawthorne; H M McKenzie; R G Sinclair; R J Simpson; G M Stewart; D I Williams
Journal:  Br Med J       Date:  1979-03-31

3.  Semicontinuous screening of a whole community for hypertension.

Authors:  J T Hart
Journal:  Lancet       Date:  1970-08-01       Impact factor: 79.321

4.  Editorial: A plea for the "naturalistic" study of medicines.

Authors:  L Lasagna
Journal:  Eur J Clin Pharmacol       Date:  1974       Impact factor: 2.953

5.  Efficacy of a combination of diuretic, beta-blocker and vasodilator in the treatment of hypertension in general practice.

Authors:  W A Forrest
Journal:  Br J Clin Pract       Date:  1978-11

6.  Significance of controlled clinical trials.

Authors:  A Liljestrand
Journal:  Eur J Clin Pharmacol       Date:  1980-10       Impact factor: 2.953

7.  Placebos and controlled trials under attack.

Authors:  L Lasagna
Journal:  Eur J Clin Pharmacol       Date:  1979-07       Impact factor: 2.953

8.  Post marketing drug surveillance, another string to the bow.

Authors:  P J Fell; N P Watson; H F O'Donnell
Journal:  Eur J Clin Pharmacol       Date:  1978-06-19       Impact factor: 2.953

9.  USE OF PROPRANOLOL (INDERAL) IN TREATMENT OF HYPERTENSION.

Authors:  B N PRICHARD; P M GILLAM
Journal:  Br Med J       Date:  1964-09-19

10.  Metoprolol with and without chlorthalidone in hypertension.

Authors:  M Kubik; M Kendall; A Ebbutt; V John
Journal:  Clin Pharmacol Ther       Date:  1979-01       Impact factor: 6.875

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