Serum concentrations of C-reactive protein and serum amyloid P component in plaice (Pleuronectes platessa L.) in relation to season and injected lipopolysaccharide.

1. Mean monthly serum levels of total protein, C-reactive protein (CRP) and serum amyloid P component (SAP) in plaice, showed no significant difference between the sexes. 2. Highest values for CRP and protein were found between June and September, with no significant seasonal variation in SAP. 3. There was no change in CRP concentration in plaice maintained for 7 days at a higher temperature of 18.5 degrees C. 4. Injection of lipopolysaccharide caused the highest value for CRP on day 1 and for the spleen index on day 5 after injection. 5. Phagocytic stimulation with carbon had no significant effect on the CRP response to endotoxin.