Literature DB >> 6839307

Cancer in relatives of patients with aplastic anemia.

N U Potter, C Sarmousakis, F P Li.   

Abstract

The risk of cancer was examined among family members of 9 patients with Fanconi's anemia. Seven cancers of diverse types were observed, as compared with the 10.4 expected (P greater than 0.05). In addition, the study of relatives of 60 patients with acquired aplastic anemia showed no unusual distribution of cancers by site and age at diagnosis. In particular, no relative in either series had acute leukemia. Methodologic issues complicate the interpretation of several published reports of excess cancers among heterozygotes of Fanconi's anemia, ataxia-telangiectasia, and xeroderma pigmentosum.

Entities:  

Mesh：

Year:  1983        PMID： 6839307     DOI： 10.1016/0165-4608(83)90025-0

Source DB:  PubMed          Journal:  Cancer Genet Cytogenet        ISSN： 0165-4608


  5 in total

Review 1.  Fanconi anaemia.

Authors:  M D Tischkowitz; S V Hodgson
Journal:  J Med Genet       Date:  2003-01       Impact factor: 6.318

2.  How high are carrier frequencies of rare recessive syndromes? Contemporary estimates for Fanconi Anemia in the United States and Israel.

Authors:  Philip S Rosenberg; Hannah Tamary; Blanche P Alter
Journal:  Am J Med Genet A       Date:  2011-07-07       Impact factor: 2.802

3.  Genetic heterogeneity among Fanconi anemia heterozygotes and risk of cancer.

Authors:  Marianne Berwick; Jaya M Satagopan; Leah Ben-Porat; Ann Carlson; Katherine Mah; Rashida Henry; Raffaella Diotti; Kelly Milton; Kanan Pujara; Tom Landers; Sat Dev Batish; José Morales; Detlev Schindler; Helmut Hanenberg; Robert Hromas; Orna Levran; Arleen D Auerbach
Journal:  Cancer Res       Date:  2007-10-01       Impact factor: 12.701

4.  Cancer incidence in relatives of British Fanconi Anaemia patients.

Authors:  Marc Tischkowitz; Douglas F Easton; Jan Ball; Shirley V Hodgson; Christopher G Mathew
Journal:  BMC Cancer       Date:  2008-09-11       Impact factor: 4.430

5.  Fanconi Anemia germline variants as susceptibility factors in aplastic anemia, MDS and AML.

Authors:  Bartlomiej Przychodzen; Hideki Makishima; Mikkael A Sekeres; Suresh Kumar Balasubramanian; Swapna Thota; Bhumika J Patel; Michael Clemente; Cassandra Hirsch; Brittney Dienes; Jaroslaw P Maciejewski
Journal:  Oncotarget       Date:  2017-12-16
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.