Literature DB >> 6838676

Serotonin content of platelets in inflammatory rheumatic diseases. Correlation with clinical activity.

J Zeller, E Weissbarth, B Baruth, H Mielke, H Deicher.   

Abstract

Significantly decreased platelet serotonin contents were measured in rheumatoid arthritis, systemic lupus erythematosus (SLE), progressive systemic sclerosis, and mixed connective tissue disease. An inverse relationship between platelet serotonin levels and clinical disease activity was observed in both rheumatoid arthritis and systemic lupus erythematosus. SLE patients with multiple organ involvement showed the lowest platelet serotonin values. No correlation was observed between platelet serotonin contents and nonsteroidal antiinflammatory drug treatment, presence of circulating platelet reactive IgG, or the amount of circulating immune complexes. The results are interpreted as indicating platelet release occurring in vivo during inflammatory episodes of the rheumatic disorders investigated.

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Year:  1983        PMID： 6838676     DOI： 10.1002/art.1780260413

Source DB:  PubMed          Journal:  Arthritis Rheum        ISSN： 0004-3591


  16 in total

1.  Long-term low dose ticlopidine treatment in rheumatoid arthritis: effects on serum sulphydryl levels, technetium index, erythrocyte sedimentation rate, and clinical disease activity.

Authors:  M G Grimaldi
Journal:  Eur J Clin Pharmacol       Date:  1985       Impact factor: 2.953

2.  Platelets release pathogenic serotonin and return to circulation after immune complex-mediated sequestration.

Authors:  Nathalie Cloutier; Isabelle Allaeys; Genevieve Marcoux; Kellie R Machlus; Benoit Mailhot; Anne Zufferey; Tania Levesque; Yann Becker; Nicolas Tessandier; Imene Melki; Huiying Zhi; Guy Poirier; Matthew T Rondina; Joseph E Italiano; Louis Flamand; Steven E McKenzie; Francine Cote; Bernhard Nieswandt; Waliul I Khan; Matthew J Flick; Peter J Newman; Steve Lacroix; Paul R Fortin; Eric Boilard
Journal:  Proc Natl Acad Sci U S A       Date:  2018-01-31       Impact factor: 11.205

3.  Increased risk of rheumatoid arthritis in patients with migraine: a population-based, propensity score-matched cohort study.

Authors:  Yi-Chia Wang; Ya-Ping Huang; Mei-Ting Wang; Hsin-I Wang; Shin-Liang Pan
Journal:  Rheumatol Int       Date:  2016-11-14       Impact factor: 2.631

Review 4.  Cytokines and other mediators in rheumatoid arthritis.

Authors:  J M Dayer; S Demczuk
Journal:  Springer Semin Immunopathol       Date:  1984

5.  Evidence for activation of platelets in the synovial fluid from patients with rheumatoid arthritis.

Authors:  G K Endresen
Journal:  Rheumatol Int       Date:  1989       Impact factor: 2.631

Review 6.  The non-haemostatic role of platelets in systemic lupus erythematosus.

Authors:  Petrus Linge; Paul R Fortin; Christian Lood; Anders A Bengtsson; Eric Boilard
Journal:  Nat Rev Rheumatol       Date:  2018-03-21       Impact factor: 20.543

7.  [Thrombocyte function and thrombocyte-associated immunoglobulins in patients with systemic lupus erythematosus and chronic polyarthritis].

Authors:  A Horn; H J Avenarius; H Deicher
Journal:  Klin Wochenschr       Date:  1990-05-04

8.  Platelet releasing activity in sera of patients with rheumatoid vasculitis.

Authors:  T J Cunningham; R L Medcalf; J D Mathews; K D Muirden
Journal:  Ann Rheum Dis       Date:  1986-01       Impact factor: 19.103

Review 9.  Platelets: active players in the pathogenesis of arthritis and SLE.

Authors:  Eric Boilard; Patrick Blanco; Peter A Nigrovic
Journal:  Nat Rev Rheumatol       Date:  2012-08-07       Impact factor: 20.543

Review 10.  Pathologic thrombopoiesis of rheumatoid arthritis.

Authors:  Ihsan Ertenli; Sedat Kiraz; M Akif Oztürk; Ibrahim c Haznedaroğlu; Ismail Celik; Meral Calgüneri
Journal:  Rheumatol Int       Date:  2003-02-11       Impact factor: 2.631
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