Treatment of chronic bacterial prostatitis by local injection of antibiotics into prostate.

Experiences with localized antibiotic treatment of chronic bacterial prostatitis by direct injection into the caudal prostate is presented. Very high antibiotic levels are found in the prostatic fluid without correlation with the time after injection. The pain and discomfort experienced by the patients during direct injection into the prostate are minimal. Hematuria and hemospermia during some weeks are practically always present after the injection. Local necrosis was not found after several histologic and electronic microscopic studies. Results demonstrated that this method deserves its place in the treatment of the hard-core group of chronic bacterial prostatitis.