Literature DB >> 6835008

Effect of hydrostatic pressure on halothane-induced depression of mitochondrial respiration.

P J Cohen.   

Abstract

Anesthetized animals are awakened when subjected to increased atmospheric pressure. Whether all phenomena associated with the anesthetic state are similarly reversed is not known. Since the anesthetic halothane produces a dose-related reversible depression of rat liver mitochondrial respiration, the effect of 51 atmospheres of pressure on the drug's action was evaluated. It is concluded that application of pressure does not antagonize the inhibition produced by this anesthetic.

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Year:  1983        PMID: 6835008     DOI: 10.1016/0024-3205(83)90872-x

Source DB:  PubMed          Journal:  Life Sci        ISSN: 0024-3205            Impact factor:   5.037


  3 in total

1.  Hyperbaric pressure does not affect the analgesia produced by nitrous oxide in the mouse.

Authors:  P J Cohen
Journal:  Can J Anaesth       Date:  1989-01       Impact factor: 5.063

2.  Effect of halothane on the replication of animal viruses.

Authors:  E Bedows; B A Davidson; P R Knight
Journal:  Antimicrob Agents Chemother       Date:  1984-06       Impact factor: 5.191

3.  Anesthetic Hypersensitivity in a Case-Controlled Series of Patients With Mitochondrial Disease.

Authors:  Vincent C Hsieh; Julie Niezgoda; Margaret M Sedensky; Charles L Hoppel; Philip G Morgan
Journal:  Anesth Analg       Date:  2021-10-01       Impact factor: 6.627

  3 in total

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