Literature DB >> 6834378

Mechanism of steroid anesthetic action: interactions of alphaxalone and delta 16-alphaxalone with bilayer vesicles.

A Makriyannis, S Fesik.   

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Year:  1983        PMID: 6834378     DOI: 10.1021/jm00358a001

Source DB:  PubMed          Journal:  J Med Chem        ISSN: 0022-2623            Impact factor:   7.446


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  6 in total

1.  Neurosteroid analogues. 15. A comparative study of the anesthetic and GABAergic actions of alphaxalone, Δ16-alphaxalone and their corresponding 17-carbonitrile analogues.

Authors:  Achintya K Bandyopadhyaya; Brad D Manion; Ann Benz; Amanda Taylor; Nigam P Rath; Alex S Evers; Charles F Zorumski; Steven Mennerick; Douglas F Covey
Journal:  Bioorg Med Chem Lett       Date:  2010-09-15       Impact factor: 2.823

2.  2012 Division of medicinal chemistry award address. Trekking the cannabinoid road: a personal perspective.

Authors:  Alexandros Makriyannis
Journal:  J Med Chem       Date:  2014-05-01       Impact factor: 7.446

3.  The Conformations of 17β-Estradiol (E2) and 17α-Estradiol as Determined by Solution NMR.

Authors:  Jianxin Guo; Richard I Duclos; V Kiran Vemuri; Alexandros Makriyannis
Journal:  Tetrahedron Lett       Date:  2010-07-07       Impact factor: 2.415

4.  Interactions between molecules of a steroid anaesthetic (alphaxalone) and ionic channels of nodal membrane in voltage-clamped myelinated nerve fibre.

Authors:  E Benoit; M R Carratù; D Mitolo-Chieppa
Journal:  Br J Pharmacol       Date:  1988-07       Impact factor: 8.739

5.  In vitro and in vivo activity of 16,17-dehydro-epipregnanolones: 17,20-bond torsional energy analysis and D-ring conformation.

Authors:  M B Bolger; S Wieland; J E Hawkinson; H Xia; R Upasani; N C Lan
Journal:  Pharm Res       Date:  1996-10       Impact factor: 4.200

6.  Neurosteroid analogues. 16. A new explanation for the lack of anesthetic effects of δ(16)-alphaxalone and identification of a δ(17(20)) analogue with potent anesthetic activity.

Authors:  Eva Stastna; Kathiresan Krishnan; Brad D Manion; Amanda Taylor; Nigam P Rath; Zi-Wei Chen; Alex S Evers; Charles F Zorumski; Steven Mennerick; Douglas F Covey
Journal:  J Med Chem       Date:  2011-05-06       Impact factor: 7.446

  6 in total

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