Literature DB >> 6833147

Studies on tomaymycin. II. Total syntheses of the antitumor antibiotics, E-and Z-tomaymycins.

Z Tozuka, H Takasugi, T Takaya.   

Abstract

The total syntheses of naturally occurring E-tomaymycin (1E) and its olefinic geometrical isomer, Z-tomaymycin (1Z) are described. The Z-isomer was found to have the same anti-bacterial activity as E-isomer (1E).

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Year:  1983        PMID： 6833147     DOI： 10.7164/antibiotics.36.276

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  3 in total

Review 1.  Biosynthesis, synthesis, and biological activities of pyrrolobenzodiazepines.

Authors:  Barbara Gerratana
Journal:  Med Res Rev       Date:  2010-06-13       Impact factor: 12.944

2.  Diversity of an uncommon elastic hypersaline microbial mat along a small-scale transect.

Authors:  Laura Espinosa-Asuar; Camila Monroy-Guzmán; David Madrigal-Trejo; Marisol Navarro-Miranda; Jazmin Sánchez-Pérez; Jhoselinne Buenrostro Muñoz; Juan Villar; Julián Felipe Cifuentes Camargo; Maria Kalambokidis; Diego A Esquivel-Hernandez; Mariette Viladomat Jasso; Ana E Escalante; Patricia Velez; Mario Figueroa; Anahi Martinez-Cardenas; Santiago Ramirez-Barahona; Jaime Gasca-Pineda; Luis E Eguiarte; Valeria Souza
Journal:  PeerJ       Date:  2022-06-20       Impact factor: 3.061

3.  Pyrrolo(l ,4)benzodiazepine Antitumor Antibiotics: Chemistry, Interaction with DNA, and Biological Implications.

Authors:  L H Hurley; D E Thurston
Journal:  Pharm Res       Date:  1984-03       Impact factor: 4.200
  3 in total

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