| Literature DB >> 6832880 |
Abstract
Pellagra secondary to antituberculous chemotherapy can result from isoniazide therapy, as well as from pyrazinamide treatment. Because of the similarity in structural formulas between pyrazinamide, isoniazide, and nicotinamide, the substrate competition is the mechanism most likely involved. The patient was cured by administration of nicotinamide during continued unchanged chemotherapy of her tuberculosis.Entities:
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Year: 1983 PMID： 6832880 DOI： 10.1111/j.1365-4362.1983.tb02114.x
Source DB: PubMed Journal: Int J Dermatol ISSN： 0011-9059 Impact factor: 2.736