Nitrofurantoin-induced pancreatitis: report of a case.

A patient with nitrofurantoin-induced pancreatitis is described, representing the first patient with this condition to be reported in the literature. The diagnosis of nitrofurantoin-induced pancreatitis was confirmed by rechallenge. The clinical and biochemical picture cleared rapidly after discontinuation of the drug. The conclusion is proffered that nitrofurantoin-induced jaundice is not always due to cholestatic hepatitis, but can result from obstruction of the common bile duct due to edema of the pancreatic head secondary to nitrofurantoin pancreatitis.