| Literature DB >> 6832367 |
G P Samokhin, M D Smirnov, V R Muzykantov, S P Domogatsky, V N Smirnov.
Abstract
The interaction of human red blood cells carrying antihuman collagen antibody with collagen-coated surfaces was studied. Avidin was used as bifunctional crosslinking agent for the attachment of antibody to the red blood cell surface. Antibody-carrying red blood cells efficiently and specifically bound to collagen-coated surface covering a significant part of the surface. The components of normal blood had an insignificant effect on red blood cell binding. A model of drug targeting to the injured sites(s) of blood vessel wall is proposed.Entities:
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Year: 1983 PMID: 6832367 DOI: 10.1016/0014-5793(83)80160-4
Source DB: PubMed Journal: FEBS Lett ISSN: 0014-5793 Impact factor: 4.124