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Literature DB >> 6832183

Effective RES blood flow changes in children with homozygous beta-thalassemia in relation to blood transfusion.

T H Karpathios, P Dimitriou, J Giamouris, P Nicolaidou, S E Antipas, N Matsaniotis.

Abstract

Denatured radioiodinated human serum albumin (DHA) clearance studies at a dose of 1 mg/kg body wt., were carried out in 16 thalassemic children, prior to and 7-10 days following blood transfusion, to investigate changes of the effective RES blood flow which might accompany the posttransfusion spleen size diminution. A statistically significant increase (P less than 0.001) of the DHA plasma clearance rate was observed 7-10 days following blood transfusion denoting an increase of the blood flow to the effective RES while at the same time the spleen diminished in size. It is suggested that changes in the effective RES blood flow in these patients are directly related to changes in the intrasplenic circulatory capacity.

Entities: Chemical Disease Species

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Year: 1983 PMID： 6832183 DOI： 10.1007/bf00263508

Source DB: PubMed Journal: Eur J Nucl Med ISSN： 0340-6997

9 in total

1. TRANSFUSION THERAPY IN COOLEY'S ANEMIA: GROWTH AND HEALTH AS RELATED TO LONG-RANGE HEMOGLOBIN LEVELS. A PROGRESS REPORT.

Authors: I J WOLMAN
Journal: Ann N Y Acad Sci Date: 1964-10-07 Impact factor: 5.691

2. Studies of the reticuloendothelial system (RES). I. Measurement of the phagocytic capacity of the RES in man and dog.

Authors: M IIO; H N WAGNER; U SCHEFFEL; B JABBOUR
Journal: J Clin Invest Date: 1963-03 Impact factor: 14.808

3. The kinetics of phagocytosis. 1. A study on the clearance of denatured bovine albumin and its competitive inhibition by denatured human albumin.

Authors: S J Normann
Journal: J Reticuloendothel Soc Date: 1973-12

4. Transfusion-induced decrease in spleen size in thalassemia major: documentation by radioisotopic scan.

Authors: R T O'Brien; H A Pearson; R P Spencer
Journal: J Pediatr Date: 1972-07 Impact factor: 4.406

5. Measurement of colloid clearance rate as an adjunct to static liver imaging.

Authors: J Miller; B L Diffey; J S Fleming
Journal: Eur J Nucl Med Date: 1979-02-01

6. 131 I-labeled colloidal human serum albumin in the study of reticuloendothelial system function. 3. Phagocytosis and catabolism compared in normal, leukemic, and immunosuppressed human subjects.

Authors: D L Palmer; D Rifkind; D W Brown
Journal: J Infect Dis Date: 1971-05 Impact factor: 5.226

7. Spleen size changes in children with homozygous beta-thalassaemia in relation to blood transfusion.

Authors: T Karpathios; A Antypas; P Dimitiriou; P Nicolaidou; A Fretzayas; T Thomaidis; N Matsaniotis
Journal: Scand J Haematol Date: 1982-03

8. Exploration of the phagocytic function of the reticuloendothelial system with heat denatured human serum albumin labeled with I131 and application to the measurement of liver blood flow, in normal man and in some pathologic conditions.

Authors: G BIOZZI; B BENACERRAF; B N HALPERN; C STIFFEL; B HILLEMAND
Journal: J Lab Clin Med Date: 1958-02

9. Colloid clearance rate changes in children with homozygous-beta-thalassemia in relation to blood transfusion.

Authors: P A Dimitriou; T E Karpathios; S E Antipas; A M Fretzayias; A G Kasfiki; K G Melissinos; N S Matsaniotis
Journal: Eur J Nucl Med Date: 1980-10

9 in total

4 in total

4. Achievement of Pre- and Post-Transfusion Hemoglobin Levels in Adult Transfusion-Dependent Beta Thalassemia: Associated Factors and Relationship to Reduction of Spleen Enlargement.

Authors: Tubagus Djumhana Atmakusuma; Edison Yantje Parulian Saragih; Wulyo Rajabto
Journal: Int J Gen Med Date: 2021-11-01