Literature DB >> 6831387

Determination of exposure to polycyclic aromatic hydrocarbons by analysis of human urine.

G Becher, A Bjørseth.   

Abstract

A method for biological monitoring of exposure to polycyclic aromatic hydrocarbons (PAH) has been developed. The analytical procedure includes extraction of PAH and PAH metabolites from urine using commercial cartridges containing C18-modified silica, reduction of metabolites to PAH by hydriodic acid and subsequent analysis of the PAH by high performance liquid chromatography with fluorescence detection. The method is applied to urine samples from an occupationally non-exposed control group and from aluminum workers with high exposure to PAH. In the control group urine extracts from smokers show a significantly higher level of PAH than from non-smokers. The high concentrations of PAH found in the working atmospheres of aluminum plants are not reflected to a corresponding extent in the excretion of PAH in urine.

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Year:  1983        PMID： 6831387     DOI： 10.1016/0304-3835(83)90168-4

Source DB:  PubMed          Journal:  Cancer Lett        ISSN： 0304-3835            Impact factor:   8.679


  9 in total

1.  An assessment of a urinary biomarker for total human environmental exposure to benzo[a]pyrene.

Authors:  T J Buckley; J M Waldman; R Dhara; A Greenberg; Z Ouyang; P J Lioy
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Review 2.  Biomarkers used in studying air pollution exposure during pregnancy and perinatal outcomes: a review.

Authors:  Gauri Desai; Li Chu; Yanjun Guo; Ajay A Myneni; Lina Mu
Journal:  Biomarkers       Date:  2017-06-21       Impact factor: 2.658

3.  Determination of parent and hydroxy PAHs in personal PM₂.₅ and urine samples collected during Native American fish smoking activities.

Authors:  Oleksii Motorykin; Jill Schrlau; Yuling Jia; Barbara Harper; Stuart Harris; Anna Harding; David Stone; Molly Kile; Daniel Sudakin; Staci L Massey Simonich
Journal:  Sci Total Environ       Date:  2014-10-30       Impact factor: 7.963

4.  Association of exposure to polycyclic aromatic hydrocarbons (estimated from job category) with concentration of 1-hydroxypyrene glucuronide in urine from workers at a steel plant.

Authors:  D Kang; N Rothman; S H Cho; H S Lim; H J Kwon; S M Kim; B Schwartz; P T Strickland
Journal:  Occup Environ Med       Date:  1995-09       Impact factor: 4.402

5.  An examination of the time course from human dietary exposure to polycyclic aromatic hydrocarbons to urinary elimination of 1-hydroxypyrene.

Authors:  T J Buckley; P J Lioy
Journal:  Br J Ind Med       Date:  1992-02

Review 6.  Polycyclic aromatic hydrocarbons and esophageal squamous cell carcinoma.

Authors:  Gholamreza Roshandel; Shahryar Semnani; Reza Malekzadeh; Sanford M Dawsey
Journal:  Arch Iran Med       Date:  2012-11       Impact factor: 1.354

7.  Biological monitoring of human exposure to coal tar. Urinary excretion of total polycyclic aromatic hydrocarbons, 1-hydroxypyrene and mutagens in psoriatic patients.

Authors:  E Clonfero; M Zordan; P Venier; M Paleologo; A G Levis; D Cottica; L Pozzoli; F J Jongeneelen; R P Bos; R B Anzion
Journal:  Int Arch Occup Environ Health       Date:  1989       Impact factor: 3.015

Review 8.  Polycyclic aromatic hydrocarbon metabolites in urine as biomarkers of exposure and effect.

Authors:  P Strickland; D Kang; P Sithisarankul
Journal:  Environ Health Perspect       Date:  1996-10       Impact factor: 9.031

9.  Short-term markers of DNA damage among roofers who work with hot asphalt.

Authors:  Berrin Serdar; Stephen Brindley; Greg Dooley; John Volckens; Elizabeth Juarez-Colunga; Ryan Gan
Journal:  Environ Health       Date:  2016-10-20       Impact factor: 5.984
  9 in total

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