Literature DB >> 6829611

Inheritance of immunoglobulin E: genetic model fitting.

S J Hasstedt, D A Meyers, D G Marsh.   

Abstract

Total serum immunoglobulin E (IgE) concentration was measured on 316 members of five pedigrees selected through breast cancer probands. Sex- and age-adjusted natural logarithm-transformed IgE level was not found to differ between individuals with breast cancer or with cancer of any site and other relatives. Likelihoods of the polygenic and of one-locus, two-allele major gene and mixed models were computed. The analysis provided evidence for the presence of a polygenic component in the determination of IgE; it did not show evidence of a major gene effect.

Entities:  

Mesh：

Substances：

Year:  1983        PMID： 6829611     DOI： 10.1002/ajmg.1320140110

Source DB:  PubMed          Journal:  Am J Med Genet        ISSN： 0148-7299


  11 in total

1.  Linkage/association study of a locus modulating total serum IgE on chromosome 14q13-24 in families with asthma.

Authors:  A H Mansur; D T Bishop; S T Holgate; A F Markham; J F J Morrison
Journal:  Thorax       Date:  2004-10       Impact factor: 9.139

Review 2.  The genetics of asthma and allergic disease: a 21st century perspective.

Authors:  Carole Ober; Tsung-Chieh Yao
Journal:  Immunol Rev       Date:  2011-07       Impact factor: 12.988

3.  Candidate gene loci in asthmatic and allergic inflammation.

Authors:  J Wilkinson; S T Holgate
Journal:  Thorax       Date:  1996-01       Impact factor: 9.139

4.  Evidence for two unlinked loci regulating total serum IgE levels.

Authors:  J Xu; R C Levitt; C I Panhuysen; D S Postma; E W Taylor; P J Amelung; K J Holroyd; E R Bleecker; D A Meyers
Journal:  Am J Hum Genet       Date:  1995-08       Impact factor: 11.025

5.  Evidence for Mendelian inheritance of serum IgE levels in Hispanic and non-Hispanic white families.

Authors:  F D Martinez; C J Holberg; M Halonen; W J Morgan; A L Wright; L M Taussig
Journal:  Am J Hum Genet       Date:  1994-09       Impact factor: 11.025

6.  Familial resemblance for immunoglobulin levels.

Authors:  I B Borecki; M McGue; J W Gerrard; M D Lebowitz; D C Rao
Journal:  Hum Genet       Date:  1994-08       Impact factor: 4.132

Review 7.  A defense of path analysis in genetic epidemiology.

Authors:  C R Cloninger; D C Rao; J Rice; T Reich; N E Morton
Journal:  Am J Hum Genet       Date:  1983-07       Impact factor: 11.025

8.  Comparisons of different sampling designs for the determination of genetic transmission mechanisms in quantitative traits.

Authors:  T L Burns; P P Moll; M A Schork
Journal:  Am J Hum Genet       Date:  1984-09       Impact factor: 11.025

9.  Sex differences in heritability of sensitization to Blomia tropicalis in asthma using regression of offspring on midparent (ROMP) methods.

Authors:  Teri A Manolio; Kathleen C Barnes; Terri H Beaty; Paul N Levett; Raana P Naidu; Alexander F Wilson
Journal:  Hum Genet       Date:  2003-08-20       Impact factor: 4.132

10.  Inheritance of total serum IgE (basal levels) in man.

Authors:  D A Meyers; T H Beaty; L R Freidhoff; D G Marsh
Journal:  Am J Hum Genet       Date:  1987-07       Impact factor: 11.025
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.