Literature DB >> 682804

Management of tinnitus aurium with lidocaine and carbamazepine.

J J Shea, M Harell.   

Abstract

At present there are two methods of management of tinnitus: one old, by masking with a noise generator, and one new, by biofeedback. Neither of these methods is convenient and neither gets at the heart of the problem. A third method, using intravenous lidocaine as a test and oral carbamazepine therapy, was developed in the Pain Clinic of the Auckland General Hospital in New Zealand. This paper will report our brief experience with these drugs in the management of tinnitus and other similar disorders. Twenty-seven patients with intractable tinnitus had a significant reduction from a test dose of intravenous lidocaine and were treated with oral carbamazepine. Of this group 1 patient (4%) had complete relief, 21 patients (78%) had partial relief, and 5 patients (18%) had no relief. Complications were few and not serious, and either disappeared spontaneously or when the carbamazepine was stopped. One patient with palatal myoclonus, refractory to all other forms of treatment, had complete relief on a small dose of carbamazepine. It may be that palatal myoclonus, hemifacial spasm, and other such clonic convulsive disorders will be amenable to the same treatment.

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Year:  1978        PMID: 682804     DOI: 10.1002/lary.1978.88.9.1477

Source DB:  PubMed          Journal:  Laryngoscope        ISSN: 0023-852X            Impact factor:   3.325


  7 in total

Review 1.  Drugs affecting the inner ear. A review of their clinical efficacy, mechanisms of action, toxicity, and place in therapy.

Authors:  C H Norris
Journal:  Drugs       Date:  1988-12       Impact factor: 9.546

2.  PHARMACOLOGICAL TREATMENTS FOR TINNITUS: NEW AND OLD.

Authors:  R Salvi; E Lobarinas; W Sun
Journal:  Drugs Future       Date:  2009       Impact factor: 0.148

Review 3.  Ménière's disease. A practical approach to management.

Authors:  G B Brookes
Journal:  Drugs       Date:  1983-01       Impact factor: 9.546

4.  Expression and localization of K channels KCNQ2 and KCNQ3 in the mammalian cochlea.

Authors:  Zhe Jin; Gui-Hua Liang; Edward C Cooper; Leif Jarlebark
Journal:  Audiol Neurootol       Date:  2008-10-01       Impact factor: 1.854

Review 5.  Emerging pharmacotherapy of tinnitus.

Authors:  Berthold Langguth; Richard Salvi; Ana Belén Elgoyhen
Journal:  Expert Opin Emerg Drugs       Date:  2009-12       Impact factor: 4.191

6.  Randomised Controlled Clinical Study of Injection Caroverine and Ginkgo Biloba Extract in Cochlear Synaptic Tinnitus.

Authors:  Rajeev Kumar Nishad; Anil Kumar Jain; Mangal Singh; Reetu Verma; Sanyogita Jain
Journal:  Indian J Otolaryngol Head Neck Surg       Date:  2019-04-13

7.  Objective Tinnitus Concomitant with Eye Blinking: A Case Report.

Authors:  Tae Hwan Kim; Ho Joon Jang; Soon Hyung Park; Sung-Il Nam
Journal:  J Audiol Otol       Date:  2015-09-16
  7 in total

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