Literature DB >> 68273

Isolation of reovirus-like agents from patients with Crohn's disease.

P J Whorwell, C A Phillips, W L Beeken, P K Little, K D Roessner.   

Abstract

220 nm filtrates of intestinal resections from 6 of 10 patients with Crohn's disease produced a cytopathic effect in WI-38 tissue-culture monolayers, whereas controls had no effect. Characterisation of the virus responsible has been completed in 3 of the 6 positive isolates and indicates that it is an R.N.A. virus, 55-60 nm in diameter, heat, ether, and acid stable, and antigenically related to Nebraska calf-diarrhoea virus. It therefore belongs to the Reoviridae family.

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Year:  1977        PMID： 68273     DOI： 10.1016/s0140-6736(77)92714-3

Source DB:  PubMed          Journal:  Lancet        ISSN： 0140-6736            Impact factor:   79.321


  27 in total

Review 1.  Viruses in the stools.

Authors:  C R Madeley
Journal:  J Clin Pathol       Date:  1979-01       Impact factor: 3.411

Review 2.  Rotavirus gastroenteritis.

Authors:  J Walker-Smith
Journal:  Arch Dis Child       Date:  1978-05       Impact factor: 3.791

3.  Hybridomas using athymic nude mouse injected with Crohn's disease (CD) tissue filtrate. Immunoreactivity of the hybridomas with CD sera.

Authors:  K M Das; M Vecchi; A Novikoff; S Mazumdar; P M Novikoff
Journal:  Am J Pathol       Date:  1990-06       Impact factor: 4.307

4.  Circulating immune complexes and disease activity in Crohn's disease.

Authors:  R Fiasse; A Z Lurhuma; C L Cambiaso; P L Masson; C Dive
Journal:  Gut       Date:  1978-07       Impact factor: 23.059

5.  Evidence for the isolation of a new virus from ulcerative colitis patients. Comparison with virus derived from Crohn's disease.

Authors:  G L Gitnick; V J Rosen; M H Arthur; S A Hertweck
Journal:  Dig Dis Sci       Date:  1979-08       Impact factor: 3.199

6.  Incidence of Crohn's disease in Cardiff between 1934-1977.

Authors:  J Mayberry; J Rhodes; L E Hughes
Journal:  Gut       Date:  1979-07       Impact factor: 23.059

7.  Search for evidence of a viral aetiology for inflammatory bowel disease.

Authors:  H H Yoshimura; M K Estes; D Y Graham
Journal:  Gut       Date:  1984-04       Impact factor: 23.059

8.  Antibodies to maize in patients with Crohn's disease, ulcerative colitis and coeliac disease.

Authors:  I W Davidson; R S Lloyd; P J Whorwell; R Wright
Journal:  Clin Exp Immunol       Date:  1979-01       Impact factor: 4.330

9.  Immune status in Crohn's disease. 4. In vitro antibody dependent cell mediated cytotoxicity in peripheral blood.

Authors:  I O Auer; E Ziemer
Journal:  Klin Wochenschr       Date:  1980-08-01

10.  Detection of immunoreactive antigen, with a monoclonal antibody to measles virus, in tissue from a patient with Crohn's disease.

Authors:  H Miyamoto; T Tanaka; N Kitamoto; Y Fukuda; T Shimoyama
Journal:  J Gastroenterol       Date:  1995-02       Impact factor: 7.527
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