Literature DB >> 6826635

The effect of attenuated vaccinia virus AS strain on N-methyl-N'-nitro-N-nitrosoguanidine-induced gastric cancer in rats.

S Arakawa, K Fukai.   

Abstract

The effect of vaccinia virus on MNNG-induced gastric cancer in rats was studied. Subcutaneous inoculation of the highly attenuated vaccinia virus AS strain at intervals of 3 days from the beginning of the experiment showed prominent antitumor activity not only against adenocarcinoma induced by MNNG in the glandular stomach but also against squamous cell carcinoma in the forestomach. Both UV-inactivated vaccinia virus and the DI strain of mammalian pathogenic vaccinia virus, from which the AS strain originated, showed no antitumor effect.

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Year:  1983        PMID： 6826635     DOI： 10.1007/bf00406921

Source DB:  PubMed          Journal:  J Cancer Res Clin Oncol        ISSN： 0171-5216            Impact factor:   4.553


  9 in total

1.  VITILIGO IN A CASE OF VACCINIA VIRUS-TREATED MELANOMA.

Authors:  K H BURDICK; W A HAWK
Journal:  Cancer       Date:  1964-06       Impact factor: 6.860

2.  Virotherapy of skin cancers. I. Clinical effect of purified vaccine lymph on skin cancers.

Authors:  Y NOGUCHI; K SAWAIZUMI; K ISHIWARA; T SAITO
Journal:  Yokohama Med Bull       Date:  1960-08

3.  An investigation into the purifying effect of a fluorocarbon on vaccinia virus.

Authors:  M A EPSTEIN
Journal:  Br J Exp Pathol       Date:  1958-08

4.  Studies on vaccinia hemagglutinin. I. On the production of vaccinia hemagglutinin in the developing chick embryo.

Authors:  I TAGAYA
Journal:  Jpn J Med Sci Biol       Date:  1954-02

5.  Further notes on the clinical application of the purified vaccine lymph (PVL).

Authors:  H YAOI
Journal:  Yokohama Med Bull       Date:  1953-02

6.  A pilgrim's progress in cancer research, 1918 to 1974: autobiographical essay.

Authors:  W Nakahara
Journal:  Cancer Res       Date:  1974-08       Impact factor: 12.701

7.  Immunotherapy of malignant melanoma with vaccinia virus.

Authors:  H H Roenigk; S Deodhar; R St Jacques; K Burdick
Journal:  Arch Dermatol       Date:  1974-05

8.  Tumour production in glandular stomach of rat by N-methyl-N'-nitro-N-nitrosoguanidine.

Authors:  T Sugimura; S Fujimura
Journal:  Nature       Date:  1967-12-02       Impact factor: 49.962

9.  Plaque formation and isolation of pure lines with poliomyelitis viruses.

Authors:  R DULBECCO; M VOGT
Journal:  J Exp Med       Date:  1954-02       Impact factor: 14.307
  9 in total
  1 in total

1.  Clinical trial of attenuated vaccinia virus AS strain in the treatment of advanced adenocarcinoma. Report on two cases.

Authors:  S Arakawa; G Hamami; K Umezu; S Kamidono; J Ishigami; S Arakawa
Journal:  J Cancer Res Clin Oncol       Date:  1987       Impact factor: 4.553
  1 in total

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