Literature DB >> 6825860

Kinetic properties of cobalt--iron hybrid hemoglobins.

M Oertle, K H Winterhalter, E E Di Iorio.   

Abstract

The replacement of O2 with CO was studied on cobalt-iron hemoglobin hybrids. Both proto- and mesocobalt hemes were used for the reconstitution. In the oxy quaternary conformation no difference is observed between alpha- and beta-subunits when only proto hemes are present in the hybrid (k4 = 30 s-1, k'4/l'4 = 2.5). If Co-meso heme is present on the beta-chains the binding properties of the partner subunit are modified (k'4/l'4 = 4).

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Year:  1983        PMID： 6825860     DOI： 10.1016/0014-5793(83)80150-1

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  2 in total

1.  Kinetics of carbon monoxide binding to phenobarbital-induced cytochrome P-450 from rat liver microsomes: a simple bimolecular process.

Authors:  M Oertle; C Richter; K H Winterhalter; E E Di Iorio
Journal:  Proc Natl Acad Sci U S A       Date:  1985-08       Impact factor: 11.205

2.  Isocyanide binding kinetics to monomeric hemoproteins. A study on the ligand partition between solvent and heme pocket.

Authors:  E E Di Iorio; K H Winterhalter; G M Giacometti
Journal:  Biophys J       Date:  1987-03       Impact factor: 4.033
  2 in total

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