Literature DB >> 6825808

alpha-Particle track autoradiography for localization of a 211At-astatinated drug.

J S Mitchell, I Brown, R N Carpenter.   

Abstract

A potential endoradiotherapeutic drug, 6-211At-astato-2-methyl-1,4-naphthoquinol bis (diphosphate salt), incorporating the alpha-emitting radio-halogen astatine-211 of half-life 7.2 h, is shown to be valuable for localization studies by means of alpha-particle track autoradiography in malignant and normal cells and tissues in the mouse with transplanted adenocarcinoma of the rectum.

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Year:  1983        PMID： 6825808     DOI： 10.1007/bf01955337

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  5 in total

1.  The accumulation, metabolism and biological effects of astatine in rats and monkeys.

Authors:  J G HAMILTON; C W ASLING; W M GARRISON; K G SCOTT
Journal:  Univ Calif Publ Pharmacol       Date:  1953-02-27

2.  6-211 At-astato-2-methyl-1,4-naphthoquinol bis (disodium phosphate): a novel alpha-emitting potential anti-tumour drug.

Authors:  I Brown
Journal:  Int J Appl Radiat Isot       Date:  1982-01

3.  A cell line from an induced carcinoma of mouse rectum.

Authors:  L M Franks; V J Hemmings
Journal:  J Pathol       Date:  1978-01       Impact factor: 7.996

4.  6-125I-iodo-2-methyl-1,4-naphthoquinol bis (diammonium phosphate) as a potential radio-halogenated anti-cancer agent: in vitro investigations and possible clinical implications.

Authors:  I Brown; R N Carpenter; J S Mitchell
Journal:  Eur J Nucl Med       Date:  1982

5.  Investigations of tritiated menadiol sodium diphosphate (T-MNDP) as a radioactive drug.

Authors:  J S Mitchell
Journal:  Br J Cancer       Date:  1974-05       Impact factor: 7.640
  5 in total
  1 in total

1.  Alpha-particle track autoradiographic study of the distribution of a [211At]-astatinated drug in normal tissues of the mouse.

Authors:  J S Mitchell; I Brown; R N Carpenter
Journal:  Experientia       Date:  1985-07-15
  1 in total

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