Literature DB >> 6824756

Two stable steady states in the Hodgkin-Huxley axons.

K Aihara, G Matsumoto.   

Abstract

Two stable steady states were found in the numerical solution of the Hodgkin-Huxley equations for the intact squid axon bathed in potassium-rich sea water with an externally applied inward current. Under the conditions the two stable steady-states exist, the Hodgkin-Huxley equations have a complex bifurcation structure including, in addition to the two stable steady-states, a stable limit cycle, two unstable equilibrium points, and one asymptotically stable equilibrium point. It was also concluded that two stable steady states can appear in the Hodgkin-Huxley axons when the leak current is comparable to the currents through the Na and K channels.

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Year:  1983        PMID: 6824756      PMCID: PMC1329016          DOI: 10.1016/S0006-3495(83)84408-7

Source DB:  PubMed          Journal:  Biophys J        ISSN: 0006-3495            Impact factor:   4.033


  10 in total

1.  Demonstration of two stable states of the nerve membrane in potassium-rich media.

Authors:  I TASAKI
Journal:  J Physiol       Date:  1959-10       Impact factor: 5.182

2.  Excitation of the squid axon membrane in isosmotic potassium chloride.

Authors:  J W MOORE
Journal:  Nature       Date:  1959-01-24       Impact factor: 49.962

3.  An anodal threshold phenomenon in the squid giant axon.

Authors:  J R SEGAL
Journal:  Nature       Date:  1958-11-15       Impact factor: 49.962

4.  The action of calcium on the electrical properties of squid axons.

Authors:  B FRANKENHAEUSER; A L HODGKIN
Journal:  J Physiol       Date:  1957-07-11       Impact factor: 5.182

5.  A quantitative description of membrane current and its application to conduction and excitation in nerve.

Authors:  A L HODGKIN; A F HUXLEY
Journal:  J Physiol       Date:  1952-08       Impact factor: 5.182

6.  Analysis of excitation process in squid giant axons under bi-ionic conditions.

Authors:  I Tasaki; L Lerman; A Watanabe
Journal:  Am J Physiol       Date:  1969-01

7.  Temporally coherent organization and instabilities in squid giant axons.

Authors:  K Aihara; G Matsumoto
Journal:  J Theor Biol       Date:  1982-04-21       Impact factor: 2.691

8.  Bifurcation of periodic solutions of Hodgkin-Huxley model for the squid giant axon.

Authors:  B Hassard
Journal:  J Theor Biol       Date:  1978-04-06       Impact factor: 2.691

9.  Calcium inward currents in internally perfused giant axons.

Authors:  H Meves; W Vogel
Journal:  J Physiol       Date:  1973-11       Impact factor: 5.182

10.  Separation of the action potential into a Na-channel spike and a K-channel spike by tetrodotoxin and by tetraethylammonium ion in squid giant axons internally perfused with dilute Na-salt solutions.

Authors:  I Inoue
Journal:  J Gen Physiol       Date:  1980-09       Impact factor: 4.086

  10 in total
  5 in total

1.  Bistability dynamics in simulations of neural activity in high-extracellular-potassium conditions.

Authors:  P J Hahn; D M Durand
Journal:  J Comput Neurosci       Date:  2001 Jul-Aug       Impact factor: 1.621

2.  On the relationship between the number of negative slope regions in the voltage-current curve of the Hodgkin-Huxley model and its parameter values.

Authors:  Y A Bedrov; G N Akoev; O E Dick
Journal:  Biol Cybern       Date:  1995-07       Impact factor: 2.086

3.  Bistable dynamics underlying excitability of ion homeostasis in neuron models.

Authors:  Niklas Hübel; Eckehard Schöll; Markus A Dahlem
Journal:  PLoS Comput Biol       Date:  2014-05-01       Impact factor: 4.475

4.  Explosive death induced by mean-field diffusion in identical oscillators.

Authors:  Umesh Kumar Verma; Amit Sharma; Neeraj Kumar Kamal; Jürgen Kurths; Manish Dev Shrimali
Journal:  Sci Rep       Date:  2017-08-11       Impact factor: 4.379

5.  Effects of maximal sodium and potassium conductance on the stability of Hodgkin-Huxley model.

Authors:  Yue Zhang; Kuanquan Wang; Yongfeng Yuan; Dong Sui; Henggui Zhang
Journal:  Comput Math Methods Med       Date:  2014-07-03       Impact factor: 2.238

  5 in total

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