Literature DB >> 6824319

Enhancement of the 7 alpha-dehydroxylase activity of a gram-positive intestinal anaerobe by flavins.

N Masuda, H Oda, S Hirano, H Tanaka.   

Abstract

The addition of flavins to the growth medium specifically enhanced the 7alpha-dehydroxylation of bile acids by anaerobically growing cultures of a Eubacterium lentum-like intestinal anaerobe, strain c-25, without an increase in cell growth. The order of the enhancement of the reaction was flavin adenine dinucleotide > flavin mononucleotide >> riboflavin.

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Year:  1983        PMID： 6824319      PMCID： PMC242272          DOI： 10.1128/aem.45.1.308-309.1983

Source DB:  PubMed          Journal:  Appl Environ Microbiol        ISSN： 0099-2240            Impact factor:   4.792


  11 in total

Review 1.  Riboflavin oversynthesis.

Authors:  A L Demain
Journal:  Annu Rev Microbiol       Date:  1972       Impact factor: 15.500

Review 2.  Microbiological transformation of bile acids.

Authors:  S Hayakawa
Journal:  Adv Lipid Res       Date:  1973

3.  Degradation of steroids by intestinal bacteria. II. Enzymes catalysing the oxidoreduction of the 3 alpha-, 7 alpha- and 12 alpha-hydroxyl groups in cholic acid, and the dehydroxylation of the 7-hydroxyl group.

Authors:  V Aries; M J Hill
Journal:  Biochim Biophys Acta       Date:  1970-05-05

4.  Characterization of a NADH:flavin oxidoreductase induced by cholic acid in a 7 alpha-dehydroxylating intestinal Eubacterium species.

Authors:  R H Lipsky; P B Hylemon
Journal:  Biochim Biophys Acta       Date:  1980-04-11

5.  Bile acid induction specificity of 7 alpha-dehydroxylase activity in an intestinal Eubacterium species.

Authors:  B A White; R L Lipsky; R J Fricke; P B Hylemon
Journal:  Steroids       Date:  1980-01       Impact factor: 2.668

6.  Characterization of a C21 neutral steroid hormone transforming enzyme, 21-dehydroxylase, in crude cell extracts of Eubacterium lentum.

Authors:  S D Feighner; V D Bokkenheuser; J Winter; P B Hylemon
Journal:  Biochim Biophys Acta       Date:  1979-07-27

7.  7alpha-Dehydroxylation of cholic acid and chenodeoxycholic acid by Clostridium leptum.

Authors:  E J Stellwag; P B Hylemon
Journal:  J Lipid Res       Date:  1979-03       Impact factor: 5.922

8.  [The significance of the bacterial steroid degradation for the etiology of large bowel cancer. IV. Deconjugation of glycocholic acid, oxidation, and reduction of cholic acid by saccharolytic Bacteroides species (author's transl)].

Authors:  R Edenharder; J Slemrova
Journal:  Zentralbl Bakteriol Orig B       Date:  1976-07

9.  Characterization of a corticosteroid 21-dehydroxylase from the intestinal anaerobic bacterium, Eubacterium lentum.

Authors:  S D Feighner; P B Hylemon
Journal:  J Lipid Res       Date:  1980-07       Impact factor: 5.922

10.  Isolation and characterization of thirteen intestinal microorganisms capable of 7 alpha-dehydroxylating bile acids.

Authors:  S Hirano; R Nakama; M Tamaki; N Masuda; H Oda
Journal:  Appl Environ Microbiol       Date:  1981-03       Impact factor: 4.792
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  2 in total

1.  7 alpha-Dehydroxylation of bile acids by resting cells of a Eubacterium lentum-like intestinal anaerobe, strain c-25.

Authors:  N Masuda; H Oda; S Hirano; M Masuda; H Tanaka
Journal:  Appl Environ Microbiol       Date:  1984-04       Impact factor: 4.792

Review 2.  Why Bile Acids Are So Important in Non-Alcoholic Fatty Liver Disease (NAFLD) Progression.

Authors:  Aline Gottlieb; Ali Canbay
Journal:  Cells       Date:  2019-10-30       Impact factor: 6.600
  2 in total

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