| Literature DB >> 6824255 |
H L Judd, D R Meldrum, L J Deftos, B E Henderson.
Abstract
Estrogen replacement therapy is one of the most controversial issues in the field of reproductive medicine. Indications for its use include hot flashes, vaginal atrophy, and risk of osteoporosis. Risk of heart disease may also be an indication but this use has not been firmly established. The role of estrogen replacement therapy in aging changes of skin needs clarification. Complications of therapy include endometrial cancer, breast cancer, hypertension, hyperlipidemia, and gallbladder disease. The last three complications presumably result from hepatic actions of estrogen replacement therapy.Entities:
Keywords: Biology; Breast Cancer; Cancer; Cardiovascular Effects; Conferences And Congresses; Diseases; Endocrine System; Endometrial Cancer; Estrogens--administraction and dosage; Estrogens--complications; Estrogens--indications; Estrogens--pharmacodynamics; Hormone Receptors; Hormones; Lipid Metabolic Effects; Lipids; Menopause; Neoplasms; Ovary; Physiology; Reproduction; Treatment
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Year: 1983 PMID: 6824255 DOI: 10.7326/0003-4819-98-2-195
Source DB: PubMed Journal: Ann Intern Med ISSN: 0003-4819 Impact factor: 25.391