Literature DB >> 6824038

Characterization of catechol-O-methyltransferase activity in human uterine decidua vera tissue.

M L Casey, P C MacDonald.   

Abstract

In the present investigation, we characterized the activity of catechol-O-methyltransferase (COMT) in homogenates prepared from human decidua vera tissue. The specific activity of COMT in decidua vera is greater than that in liver and myometrium and much greater than that in adipose tissue and erythrocytes. The specific activity of COMT in decidua vera obtained at term was significantly greater (p less than 0.001) than that obtained early in gestation. However, we do not as yet ascribe physiologic significance to this finding since the period of time between delivery of the tissue and assay of the enzyme activity may have varied between the two groups.

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Year:  1983        PMID： 6824038     DOI： 10.1016/0002-9378(83)90316-2

Source DB:  PubMed          Journal:  Am J Obstet Gynecol        ISSN： 0002-9378            Impact factor:   8.661


  6 in total

1.  Elevated expression of catechol-O-methyltransferase is associated with labor and increased prostaglandin E(2) production by human fetal membranes.

Authors:  Hassan Harirah; Chandrasekhar Thota; Melissa J Wentz; Wahiduz Zaman; Ayman Al-Hendy
Journal:  Am J Obstet Gynecol       Date:  2009-08-07       Impact factor: 8.661

2.  Regulation of catechol-O-methyltransferase expression in human myometrial cells.

Authors:  Melissa J Wentz; Mohammad Jamaluddin; Robert E Garfield; Ayman Al-Hendy
Journal:  Obstet Gynecol       Date:  2006-12       Impact factor: 7.661

3.  Preeclampsia: 2-methoxyestradiol induces cytotrophoblast invasion and vascular development specifically under hypoxic conditions.

Authors:  Soo Bong Lee; Amy P Wong; Keizo Kanasaki; Yong Xu; Vivek K Shenoy; Thomas F McElrath; George M Whitesides; Raghu Kalluri
Journal:  Am J Pathol       Date:  2010-01-14       Impact factor: 4.307

4.  A low COMT activity haplotype is associated with recurrent preeclampsia in a Norwegian population cohort (HUNT2).

Authors:  L T Roten; M H Fenstad; S Forsmo; M P Johnson; E K Moses; R Austgulen; F Skorpen
Journal:  Mol Hum Reprod       Date:  2011-02-25       Impact factor: 4.025

5.  Apolipoprotein A1 mimetic peptide ATI-5261 reverses arterial stiffness at late pregnancy and early postpartum in a COMT-/- mouse model of preeclampsia.

Authors:  Shutan Liao; Hao Wu; Ruiying Chen
Journal:  Clin Hypertens       Date:  2018-09-15

6.  Effects of estradiol on HIF-1α expression and trophoblast differentiation in first trimester villous explant cultures.

Authors:  Geum Joon Cho; Lyn Hwa Lee; Bona Lee; Jaeeun Lee; Ki-Hoon Ahn; Soon-Cheol Hong; Hai-Joong Kim; Min-Jeong Oh
Journal:  Obstet Gynecol Sci       Date:  2017-12-11
  6 in total

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