Literature DB >> 6823722

Diagnosis and management of asymptomatic renal cell carcinomas in von Hippel-Lindau syndrome.

E Levine, J W Weigel, D L Collins.   

Abstract

Renal cell carcinomas occurred in 6 of 17 subjects with the von Hippel-Lindau syndrome (HLS). In 4 patients, the tumors were discovered by abdominal computed tomography (CT) during a prospective study. Abdominal CT is recommended as a safe and accurate method for screening patients with HLS for renal cell carcinoma. Renal cell carcinoma in HLS tends to be multifocal and bilateral. Because of this, it is recommended that the tumors be treated by surgical enucleation rather than by more extensive surgical procedures which might ultimately lead to the need for dialysis.

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Year:  1983        PMID： 6823722     DOI： 10.1016/0090-4295(83)90010-9

Source DB:  PubMed          Journal:  Urology        ISSN： 0090-4295            Impact factor:   2.649


  5 in total

1.  Von Hippel-Lindau disease in a Newfoundland kindred.

Authors:  J S Green; M I Bowmer; G J Johnson
Journal:  CMAJ       Date:  1986-01-15       Impact factor: 8.262

2.  Molecular aspects of renal cell carcinoma: a review.

Authors:  Hari Koul; Jung-Sik Huh; Kyle O Rove; Luiza Crompton; Sweaty Koul; Randall B Meacham; Fernando J Kim
Journal:  Am J Cancer Res       Date:  2010-12-18       Impact factor: 6.166

3.  VHL c.505 T>C mutation confers a high age related penetrance but no increased overall mortality.

Authors:  B U Bender; C Eng; M Olschewski; D P Berger; J Laubenberger; C Altehöfer; G Kirste; M Orszagh; V van Velthoven; H Miosczka; D Schmidt; H P Neumann
Journal:  J Med Genet       Date:  2001-08       Impact factor: 6.318

4.  Statistical analysis of the two stage mutation model in von Hippel-Lindau disease, and in sporadic cerebellar haemangioblastoma and renal cell carcinoma.

Authors:  E R Maher; J R Yates; M A Ferguson-Smith
Journal:  J Med Genet       Date:  1990-05       Impact factor: 6.318

5.  Two single nucleotide polymorphisms in the von Hippel-Lindau tumor suppressor gene in Taiwanese with renal cell carcinoma.

Authors:  Wen-Chung Wang; Mei-Hua Tsou; Hui-Ju Chen; Wei-Fang Hsu; Yen-Chein Lai
Journal:  BMC Res Notes       Date:  2014-09-12
  5 in total

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