Literature DB >> 6822500

Acetylation and calcium-dependent phosphorylation of histone H3 in nuclei from butyrate-treated HeLa cells.

J P Whitlock, D Galeazzi, H Schulman.   

Abstract

In HeLa nuclei, 1 microM Ca2+ stimulates 3-fold the phosphorylation of histone H3. Prior treatment of cells with Na butyrate increases the degree of H3 phosphorylation and reveals a correlation between the extents of H3 acetylation and phosphorylation. Acetylation of H3 increases its accessibility to the calcium-dependent kinase. Phosphorylation of H3 occurs at a serine residue located in the trypsin-sensitive region of the protein. Brief digestion of nuclei with DNase I preferentially releases the phosphorylated form of H3 from chromatin.

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Year:  1983        PMID： 6822500

Source DB:  PubMed          Journal:  J Biol Chem        ISSN： 0021-9258            Impact factor:   5.157


  10 in total

1.  Phospho-acetylation of histone H3 in the amygdala after acute lithium chloride.

Authors:  Bumsup Kwon; Thomas A Houpt
Journal:  Brain Res       Date:  2010-03-25       Impact factor: 3.252

2.  Activation of the multifunctional Ca2+/calmodulin-dependent protein kinase by autophosphorylation: ATP modulates production of an autonomous enzyme.

Authors:  L L Lou; S J Lloyd; H Schulman
Journal:  Proc Natl Acad Sci U S A       Date:  1986-12       Impact factor: 11.205

3.  The beta-globin domain in immature chicken erythrocytes: enhanced solubility is coincident with histone hyperacetylation.

Authors:  D A Nelson; R C Ferris; D E Zhang; C R Ferenz
Journal:  Nucleic Acids Res       Date:  1986-02-25       Impact factor: 16.971

4.  Cooperation between phosphorylation and acetylation processes in transcriptional control.

Authors:  E Espinos; A Le Van Thaï; C Pomiès; M J Weber
Journal:  Mol Cell Biol       Date:  1999-05       Impact factor: 4.272

5.  Mitogen-stimulated phosphorylation of histone H3 is targeted to a small hyperacetylation-sensitive fraction.

Authors:  M J Barratt; C A Hazzalin; E Cano; L C Mahadevan
Journal:  Proc Natl Acad Sci U S A       Date:  1994-05-24       Impact factor: 11.205

6.  Butyrate and trichostatin A effects on the proliferation/differentiation of human intestinal epithelial cells: induction of cyclin D3 and p21 expression.

Authors:  S Siavoshian; J P Segain; M Kornprobst; C Bonnet; C Cherbut; J P Galmiche; H M Blottière
Journal:  Gut       Date:  2000-04       Impact factor: 23.059

Review 7.  Butyrate and the colonocyte. Implications for neoplasia.

Authors:  O C Velázquez; H M Lederer; J L Rombeau
Journal:  Dig Dis Sci       Date:  1996-04       Impact factor: 3.199

8.  Requirement of Ca2+ and CaMKII for Stat1 Ser-727 phosphorylation in response to IFN-gamma.

Authors:  Jayasree S Nair; Christopher J DaFonseca; Agneta Tjernberg; Wei Sun; James E Darnell; Brian T Chait; J Jillian Zhang
Journal:  Proc Natl Acad Sci U S A       Date:  2002-04-23       Impact factor: 11.205

Review 9.  Nuclear protein kinases.

Authors:  H R Matthews; V D Huebner
Journal:  Mol Cell Biochem       Date:  1984       Impact factor: 3.396

10.  Regulation of the phosphorylation of human pharyngeal cell proteins by group A streptococcal surface dehydrogenase: signal transduction between streptococci and pharyngeal cells.

Authors:  V Pancholi; V A Fischetti
Journal:  J Exp Med       Date:  1997-11-17       Impact factor: 14.307
  10 in total

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