Multicentric giant follicular lymph node hyperplasia. Favorable response to radiotherapy.

Angiofollicular lymph node hyperplasia is a disease of unknown etiology in which two distinct histologic forms are recognized: the hyalin vascular and the plasma-cell types. Up to the current time only a few multicentric cases have been described. The authors describe an unusual case of the multicentric type, which furthermore showed an excellent response to low dosis radiotherapy. Complete, lasting remission was induced and the patient became asymptomatic.