Literature DB >> 681981

3,3'-Iminodipropionitrile induced centrifugal segmental demyelination and onion bulb formation.

M Shimono, K Izumi, V Kuroiwa.   

Abstract

Centrifugal segmental demyelination extended from the proximal to the distal portion, and onion bulb formation in the extraspinal ventral root occurred following the axonal lesion of the intraspinal ventral root induced by 3,3'-iminodipropionitrile. These results suggest that axonal factors may be responsible to segmental demyelination and onion bulb formation.

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Year:  1978        PMID: 681981     DOI: 10.1097/00005072-197807000-00002

Source DB:  PubMed          Journal:  J Neuropathol Exp Neurol        ISSN: 0022-3069            Impact factor:   3.685


  5 in total

1.  Neurotoxicity of sodium cyanate. New pathological and ultrastructural observations in Maccaca nemestrina.

Authors:  I Tellez; D Johnson; R L Nagel; A Cerami
Journal:  Acta Neuropathol       Date:  1979-06-15       Impact factor: 17.088

2.  Communicating hydrocephalus in rodents treated with beta,beta'-iminodipropionitrile (IDPN).

Authors:  M G Fiori; L R Sharer; H E Lowndes
Journal:  Acta Neuropathol       Date:  1985       Impact factor: 17.088

3.  Onion bulb formation in the initial complex of neurons in human dorsal root ganglion: their significance and alterations in amyotrophic lateral sclerosis.

Authors:  S Murayama; T W Bouldin; K Suzuki
Journal:  Acta Neuropathol       Date:  1991       Impact factor: 17.088

4.  Ethylene oxide polyneuropathy: clinical follow-up study with morphometric and electron microscopic findings in a sural nerve biopsy.

Authors:  J M Schröder; M Hoheneck; J Weis; H Deist
Journal:  J Neurol       Date:  1985       Impact factor: 4.849

5.  Myelin-associated glycoprotein and myelinating Schwann cell-axon interaction in chronic B,B'-iminodipropionitrile neuropathy.

Authors:  B D Trapp; R H Quarles; J W Griffin
Journal:  J Cell Biol       Date:  1984-04       Impact factor: 10.539

  5 in total

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