Literature DB >> 6819339

A comparison of phenytoin and pheneturide in patients with epilepsy: a double-blind cross-over trial.

F B Gibberd, D M Park, G Scott, M J Gawel, D E Fry, N G Page, C Engler, J R English, F C Rose.   

Abstract

A double-blind cross-over trial between pheneturide and phenytoin in ninety-four outpatients with epilepsy is described. There was no significant difference between the frequency of seizures in the two groups. The difficulties in comparing two anticonvulsants of similar efficacy are discussed particularly in relation to ethical problems, the selection of patients and trial design.

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Year:  1982        PMID: 6819339      PMCID: PMC491693          DOI: 10.1136/jnnp.45.12.1113

Source DB:  PubMed          Journal:  J Neurol Neurosurg Psychiatry        ISSN: 0022-3050            Impact factor:   10.154


  4 in total

1.  Pheneturide in epilepsy: preliminary communication.

Authors:  J C Bowe; B J Shersby
Journal:  Br J Clin Pract       Date:  1973-05

2.  Comparative trial of diazepam and pheneturide in treatment of epilepsy.

Authors:  H I Hershon; M Parsonage
Journal:  Lancet       Date:  1969-10-25       Impact factor: 79.321

3.  A rapid micro-method for determining four anti-convulsant drugs by gas-liquid chromatography.

Authors:  A S Papadopoulos; E M Baylis; D E Fry; V Marks
Journal:  Clin Chim Acta       Date:  1973-10-12       Impact factor: 3.786

4.  Treatment of intractable temporal lobe epilepsy with pheneturide.

Authors:  C J Vas; M J Parsonage
Journal:  Acta Neurol Scand       Date:  1967       Impact factor: 3.209

  4 in total
  1 in total

1.  The comparative efficacy of antiepileptic drugs for partial and tonic-clonic seizures.

Authors:  D Chadwick; D M Turnbull
Journal:  J Neurol Neurosurg Psychiatry       Date:  1985-11       Impact factor: 10.154

  1 in total

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