Literature DB >> 6819294

Effect of calcium ion on the release of gamma-aminobutyric acid from synaptosomal fraction.

T Asakura, M Hoshino, T Kobayashi.   

Abstract

Brain synaptosomes released endogenous gamma-aminobutyric acid (GABA) in response to Ca2+. The release of GABA in response to 2.5 mM Ca2+ increased linearly with log[K+]0, showing that a membrane potential-dependent Ca2+ channel limits the GABA release. In the presence of Ca2+ ionophore, A23187, GABA release increased linearly with log[Ca2+]0 without altering the membrane potential of synaptosomes.

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Year:  1982        PMID: 6819294     DOI: 10.1093/oxfordjournals.jbchem.a134122

Source DB:  PubMed          Journal:  J Biochem        ISSN: 0021-924X            Impact factor:   3.387


  1 in total

1.  Release of acetylcholine from rat brain synaptosomes by various agents in the absence of external calcium ions.

Authors:  V Adam-Vizi; E Ligeti
Journal:  J Physiol       Date:  1984-08       Impact factor: 5.182

  1 in total

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