Literature DB >> 6819096

Antimicrobial susceptibility of gonococci isolated in the Central African Republic.

R Widy-Wirski, J D'Costa, J Biddle, S Brown.   

Abstract

Using agar dilution techniques, we determined the minimum inhibitory concentrations (MIC) of 11 antimicrobials for 70 isolates of Neisseria gonorrhoeae obtained in Bangui, Central African Republic. These gonococci were found to be fairly susceptible to commonly used antibiotics: only 3 isolates (4%) had a penicillin MIC >/= 1.0 mug/ml and 6 (9%) had a tetracycline MIC >/= 2.0 mug/ml. With regard to other antibiotics, 54 isolates (77%) had an erythromycin MIC >/= 0.25 mug/ml, all had a spectinomycin MIC </= 16 mug/ml, and 32 (46%) had a sulfamethoxazole/trimethoprim MIC >/= 9.5/0.5 mug/ml. None of these isolates produced penicillinase.This study has helped to provide a rational basis for establishing national gonorrhoea treatment recommendations in the Central African Republic.

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Year:  1982        PMID: 6819096      PMCID: PMC2535975     

Source DB:  PubMed          Journal:  Bull World Health Organ        ISSN: 0042-9686            Impact factor:   9.408


  5 in total

1.  Trends and seasonality of antibiotic resistance of Neisseria gonorrhoeae.

Authors:  H W Jaffe; A A Zaidi; C Thornsberry; G H Reynolds; P J Wiesner
Journal:  J Infect Dis       Date:  1977-11       Impact factor: 5.226

2.  Consumption of antibiotics in Greenland, 1964-70. IV. Changes in the sensitivity of N. gonorrhoeae to antibiotics.

Authors:  G A Olsen
Journal:  Br J Vener Dis       Date:  1973-02

Review 3.  Pelvic inflammatory disease and its consequences in the developing world.

Authors:  D G Muir; M A Belsey
Journal:  Am J Obstet Gynecol       Date:  1980-12-01       Impact factor: 8.661

Review 4.  Microbiologic techniques for the diagnosis of pelvic inflammatory disease in developing countries.

Authors:  A O Osoba
Journal:  Am J Obstet Gynecol       Date:  1980-12-01       Impact factor: 8.661

Review 5.  Problems and approaches in the surveillance and control of sexually transmitted agents associated with pelvic inflammatory disease in Africa.

Authors:  H Nsanze
Journal:  Am J Obstet Gynecol       Date:  1980-12-01       Impact factor: 8.661

  5 in total
  3 in total

1.  Auxotypes and serogroups of penicillinase producing and non-producing strains of Neisseria gonorrhoeae isolated in Franceville, Gabon.

Authors:  F Yvert; E Frost; M Guibourdenche; J Y Riou; B Ivanoff
Journal:  Genitourin Med       Date:  1985-04

2.  Susceptibility to antimicrobials of Neisseria gonorrhoeae isolated in Singapore: implications on the need for more effective treatment regimens and control strategies.

Authors:  E H Sng; A L Lim; K L Yeo
Journal:  Br J Vener Dis       Date:  1984-12

3.  Treatment of gonorrhoea in males in the Central African Republic with spectinomycin and procaine penicillin.

Authors:  A Meheus; R Widy-Wirski; J D'Costa; E Van Dyck; R Delgadillo; P Piot
Journal:  Bull World Health Organ       Date:  1984       Impact factor: 9.408

  3 in total

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