Literature DB >> 6819060

[Reduction of platelet serotonin in major depression (endogenous depression)].

H L Kim, O Plaisant, M Leboyer, C Gay, L Kamal, M A Devynck, P Meyer.   

Abstract

Serum serotonin (5-HT) levels were measured in several patients with psychiatric disorders using high pressure liquid chromatography with electrochemical detection. A marked reduction in 5-HT levels was found in male and female patients with major depressive disorder, as compared to controls, but not in dysthymic disorder. These modifications may constitute biochemical changes suggestive of major depressive disorders; they could not be attributed to chronic antidepressant treatment.

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Year:  1982        PMID: 6819060

Source DB:  PubMed          Journal:  C R Seances Acad Sci III        ISSN: 0249-6313


  3 in total

1.  Human depression: a new approach in quantitative psychiatry.

Authors:  Massimo Cocchi; Lucio Tonello; Mark M Rasenick
Journal:  Ann Gen Psychiatry       Date:  2010-06-03       Impact factor: 3.455

2.  Fatty acids, membrane viscosity, serotonin and ischemic heart disease.

Authors:  Massimo Cocchi; Lucio Tonello; Giovanni Lercker
Journal:  Lipids Health Dis       Date:  2010-09-08       Impact factor: 3.876

3.  Depression, osteoporosis, serotonin and cell membrane viscosity between biology and philosophical anthropology.

Authors:  Massimo Cocchi; Lucio Tonello; Fabio Gabrielli; Massimo Pregnolato
Journal:  Ann Gen Psychiatry       Date:  2011-03-30       Impact factor: 3.455

  3 in total

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