Literature DB >> 6817479

A primary screen for drugs to prevent transmission of Chagas's disease during blood transfusion.

B Cover, W E Gutteridge.   

Abstract

This paper describes how Microslide tubes can be used as the basis for a quick, simple, inexpensive screen to test for compounds which might prevent the transmission of Chagas's disease as a result of blood transfusion. The test uses Trypanosoma cruzi-infected mouse blood and requires only very small amounts of compound. The screen identifies compounds known to be active against blood trypomastigotes in vitro at 4 degrees C, and is apparently free of false negative and positive results.

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Year:  1982        PMID: 6817479     DOI: 10.1016/0035-9203(82)90228-0

Source DB:  PubMed          Journal:  Trans R Soc Trop Med Hyg        ISSN: 0035-9203            Impact factor:   2.184


  3 in total

1.  Efficient technique for screening drugs for activity against Trypanosoma cruzi using parasites expressing beta-galactosidase.

Authors:  F S Buckner; C L Verlinde; A C La Flamme; W C Van Voorhis
Journal:  Antimicrob Agents Chemother       Date:  1996-11       Impact factor: 5.191

2.  In Vitro and In Vivo Anti-Toxoplasma Activities of Dracocephalum kotschyi Extract in Experimental Models of Acute Toxoplasmosis.

Authors:  Mustafa Ghanadian; Faham Khamesipour; Seyed Hossein Hejazi; Seyed Mostafa Razavi; Hassan Sadraei; Fatemeh Namdar
Journal:  Acta Parasitol       Date:  2021-11-20       Impact factor: 1.440

3.  In vitro anti-Toxoplasma gondii activity of root extract/fractions of Eurycoma longifolia Jack.

Authors:  Nowroji Kavitha; Rahmah Noordin; Kit-Lam Chan; Sreenivasan Sasidharan
Journal:  BMC Complement Altern Med       Date:  2012-07-10       Impact factor: 3.659

  3 in total

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