Literature DB >> 6816252

Comparative effect of lipoxygenase products of arachidonic acid on rat aortic smooth muscle cell migration.

J Nakao, T Ooyama, H Ito, W C Chang, S Murota.   

Abstract

We investigated the effects of mono-hydroxyeicosatetraenoic acids (HETEs) and N-formyl-methionyl-leucyl-phenylalanine (F-Met-Leu-Phe) on rat aortic smooth muscle cell migration in modified Boyden chambers. 12-HETE showed the most potent stimulatory effect on smooth muscle cell migration among the mono-HETEs tested. The optimal concentrations for cell migration were 3 X 10(-15) and 3 X 10(-13) g/ml for 12-HETE and 10(-8) g/ml for 15-HETE, 5-HETE and F-Met-Leu-Phe were inactive with these cells. As 12-HETE is biosynthesized from arachidonic acid by the 12-lipoxygenase pathway in platelets and macrophages, and 15-HETE by the 15-lipoxygenase pathway in granulocytes, the present results indicate an important role for such cells in the early phase of atherosclerosis.

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Year:  1982        PMID： 6816252     DOI： 10.1016/0021-9150(82)90008-9

Source DB:  PubMed          Journal:  Atherosclerosis        ISSN： 0021-9150            Impact factor:   5.162


  19 in total

Review 1.  Did the antioxidant trials fail to validate the oxidation hypothesis?

Authors:  S Parthasarathy; N Khan-Merchant; M Penumetcha; B V Khan; N Santanam
Journal:  Curr Atheroscler Rep       Date:  2001-09       Impact factor: 5.113

2.  Two single nucleotide polymorphisms in ALOX15 are associated with risk of coronary artery disease in a Chinese Han population.

Authors:  Kai Zhang; Yuan-yuan Wang; Qi-ji Liu; Hui Wang; Fang-fang Liu; Zhi-yong Ma; Yao-qin Gong; Li Li
Journal:  Heart Vessels       Date:  2010-07-31       Impact factor: 2.037

3.  The effects of leukocyte-type 12/15-lipoxygenase on Id3-mediated vascular smooth muscle cell growth.

Authors:  Angela M Taylor; Ross Hanchett; Rama Natarajan; Catherine C Hedrick; Scott Forrest; Jerry L Nadler; Coleen A McNamara
Journal:  Arterioscler Thromb Vasc Biol       Date:  2005-07-21       Impact factor: 8.311

4.  Colocalization of 15-lipoxygenase mRNA and protein with epitopes of oxidized low density lipoprotein in macrophage-rich areas of atherosclerotic lesions.

Authors:  S Ylä-Herttuala; M E Rosenfeld; S Parthasarathy; C K Glass; E Sigal; J L Witztum; D Steinberg
Journal:  Proc Natl Acad Sci U S A       Date:  1990-09       Impact factor: 11.205

5.  Angiotensin II-induced vascular smooth muscle cell migration and growth are mediated by cytochrome P450 1B1-dependent superoxide generation.

Authors:  Fariborz A Yaghini; Chi Young Song; Eduard N Lavrentyev; Hafiz U B Ghafoor; Xiao R Fang; Anne M Estes; William B Campbell; Kafait U Malik
Journal:  Hypertension       Date:  2010-05-03       Impact factor: 10.190

6.  Cloning and sequence analysis of the cDNA for arachidonate 12-lipoxygenase of porcine leukocytes.

Authors:  T Yoshimoto; H Suzuki; S Yamamoto; T Takai; C Yokoyama; T Tanabe
Journal:  Proc Natl Acad Sci U S A       Date:  1990-03       Impact factor: 11.205

7.  Deletion of soluble epoxide hydrolase enhances coronary reactive hyperemia in isolated mouse heart: role of oxylipins and PPARγ.

Authors:  Ahmad Hanif; Matthew L Edin; Darryl C Zeldin; Christophe Morisseau; Mohammed A Nayeem
Journal:  Am J Physiol Regul Integr Comp Physiol       Date:  2016-08-03       Impact factor: 3.619

8.  Possible mechanism to induce protein kinase C-dependent arterial smooth muscle contraction after subarachnoid haemorrhage.

Authors:  S Ohta; J Nishihara; Y Oka; H Todo; Y Kumon; S Sakaki
Journal:  Acta Neurochir (Wien)       Date:  1995       Impact factor: 2.216

9.  Cloning of the cDNA for human 12-lipoxygenase.

Authors:  T Izumi; S Hoshiko; O Rådmark; B Samuelsson
Journal:  Proc Natl Acad Sci U S A       Date:  1990-10       Impact factor: 11.205

10.  Focal toxicity of oxysterols in vascular smooth muscle cell culture. A model of the atherosclerotic core region.

Authors:  J R Guyton; B L Black; C L Seidel
Journal:  Am J Pathol       Date:  1990-08       Impact factor: 4.307
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