Literature DB >> 6816201

The isolation and transplantation of foetal mouse proislets.

C J Simeonovic, K J Lafferty.   

Abstract

A method is described for the isolation of "proislets' from mouse foetal pancreas. Histologically, isolated proislets are composed of undifferentiated tissue which does not stain with aldehyde fuchsin. Following isotransplantation, proislets develop into well differentiated islets with beta cell granulation. In addition, isografts consisting of proislets harvested from 8 foetal mouse pancreases have the functional capacity to reverse Streptozotocin-induced diabetes. Proislets appear to represent foetal precursor islet tissue.

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Mesh：

Year:  1982        PMID： 6816201     DOI： 10.1038/icb.1982.42

Source DB:  PubMed          Journal:  Aust J Exp Biol Med Sci        ISSN： 0004-945X


  5 in total

1.  Fetal pancreas as a donor organ.

Authors:  J Brown; J A Danilovs; W R Clark; Y S Mullen
Journal:  World J Surg       Date:  1984-04       Impact factor: 3.352

2.  Theory and practice of immunoregulation by tissue treatment prior to transplantation.

Authors:  K J Lafferty; S J Prowse
Journal:  World J Surg       Date:  1984-04       Impact factor: 3.352

3.  Nonenzymic in vitro isolation of perinatal islets of Langerhans.

Authors:  O D Hegre; S Marshall; B A Schulte; G E Hickey; F Williams; R L Sorenson; J R Serie
Journal:  In Vitro       Date:  1983-08

4.  Nonenzymatic isolation and culture of adult islets from atrophic pancreata of copper-deficient rats: a morphologic analysis.

Authors:  C Weaver; R L Sorenson; B Kobienia
Journal:  In Vitro Cell Dev Biol       Date:  1988-02

5.  Pancreatic islet transplantation--experimental experience and clinical potential.

Authors:  K J Lafferty
Journal:  West J Med       Date:  1985-12
  5 in total

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