| Literature DB >> 6814930 |
Abstract
MK-801, phenobarbital and clonazepam blocked convulsions elicited in mice by bicuculline. Treatment with Ro 15-1788 antagonized the anticonvulsant action of clonazepam, but not MK-801 or phenobarbital. The anticonflict effect in the rat of chlordiazepoxide, but not MK-801, was antagonized by Ro 15-1788. Despite having certain benzodiazepine-like effects in vivo, MK-801 does not act directly or indirectly via receptors for benzodiazepines.Entities:
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Year: 1982 PMID： 6814930 DOI： 10.1016/0014-2999(82)90167-4
Source DB: PubMed Journal: Eur J Pharmacol ISSN： 0014-2999 Impact factor: 4.432