Literature DB >> 6814505

Inducible DNA repair enzymes involved in the adaptive response to alkylating agents.

T Lindahl, P Karran, B Demple, B Sedgwick, A Harris.   

Abstract

Two different DNA repair enzymes are induced in E. coli by methylating agents: a methyltransferase acting on 0(6)-methylguanine residues, and a DNA glycosylate for N-methylated purines. The properties of the homogeneous methyltransferase are described.

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Year:  1982        PMID： 6814505     DOI： 10.1016/s0300-9084(82)80091-6

Source DB:  PubMed          Journal:  Biochimie        ISSN： 0300-9084            Impact factor:   4.079


  4 in total

1.  Alkylating agent resistance: in vitro studies with human cell lines.

Authors:  E Frei; C A Cucchi; A Rosowsky; R Tantravahi; S Bernal; T J Ervin; R M Ruprecht; W A Haseltine
Journal:  Proc Natl Acad Sci U S A       Date:  1985-04       Impact factor: 11.205

2.  Hydroxyurea potentiation of the antineoplastic activity of cyclophosphamide and 4'-(9-acridinylamino)methanesulfon-M-anisidide (AMSA) in the brown Norway rat myelocytic leukemia model.

Authors:  W P Vaughan; C Holm; K Cordel
Journal:  Cancer Chemother Pharmacol       Date:  1989       Impact factor: 3.333

3.  Novobiocin enhances alkylating agent cytotoxicity and DNA interstrand crosslinks in a murine model.

Authors:  J P Eder; B A Teicher; S A Holden; K N Cathcart; L E Schnipper
Journal:  J Clin Invest       Date:  1987-05       Impact factor: 14.808

4.  SV40-induced transformation and T-antigen production is enhanced in normal and repair-deficient human fibroblasts after pretreatment of cells with UV light.

Authors:  R Hagedorn; H W Thielmann; H Fischer; C H Schroeder
Journal:  J Cancer Res Clin Oncol       Date:  1983       Impact factor: 4.553
  4 in total

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