| Literature DB >> 6814504 |
Abstract
The sensitivity of internal and terminal apurinic/apyrimidinic (AP) sites to alkaline hydrolysis and beta-elimination is described. The symmetric and asymmetric modes of endonucleolytic hydrolysis by specific AP endonucleases are compared and the discrimination between their non-enzymatic and catalytic mechanism is discussed.Mesh:
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Year: 1982 PMID: 6814504 DOI: 10.1016/s0300-9084(82)80090-4
Source DB: PubMed Journal: Biochimie ISSN: 0300-9084 Impact factor: 4.079