Literature DB >> 6812506

Valproic acid and immune thrombocytopenia.

R D Barr, S A Copeland, M L Stockwell, N Morris, J C Kelton.   

Abstract

During the course of a prospective serial study over a period of one year, findings compatible with immune-mediated thrombocytolysis accompanied the administration of valproic acid in about half of 45 children with epilepsy. Thrombocytopenia occurred in 15 and neutropenia in 12 patients, but was transient and self-limiting in each. The association is probably one of cause and effect, and it may reflect the structural similarity between valproic acid and constituents of cell membranes.

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Year:  1982        PMID： 6812506      PMCID： PMC1627777          DOI： 10.1136/adc.57.9.681

Source DB:  PubMed          Journal:  Arch Dis Child        ISSN： 0003-9888            Impact factor:   3.791


  14 in total

1.  Letter: Sodium valproate and platelet function.

Authors:  H von Voss; C Petrich; D Karch; H U Schulz; U Göbel
Journal:  Br Med J       Date:  1976-07-17

2.  IgM platelet autoantibody due to sodium valproate.

Authors:  R M Sandler; C Emberson; G E Roberts; D Voak; J Darnborough; A F Heeley
Journal:  Br Med J       Date:  1978-12-16

3.  Sodium valproate and platelet function.

Authors:  S G Richardson; D J Fletcher; P M Jeavons; J Stuart
Journal:  Br Med J       Date:  1976-01-24

4.  The direct assay for platelet-associated IgG (PAIgG): lack of association between antibody level and platelet size.

Authors:  J G Kelton; P B Neame; J Bishop; M Ali; J Gauldie; J Hirsh
Journal:  Blood       Date:  1979-01       Impact factor: 22.113

5.  Sodium valproate and thrombocytopenia.

Authors:  D A Winfield; P Benton; M L Espir; L J Arthur
Journal:  Br Med J       Date:  1976-10-23

6.  Sodium valproate and platelet-count.

Authors:  R E Raworth; G Birchall
Journal:  Lancet       Date:  1978-03-25       Impact factor: 79.321

7.  Thrombocytopenia found uncommonly during heparin therapy.

Authors:  P J Powers; D Cuthbert; J Hirsh
Journal:  JAMA       Date:  1979-06-01       Impact factor: 56.272

8.  [Blood coagulation changes through dipropyl-acetic-acid (Ergenyl)].

Authors:  A H Sutor; C Jesdinsky-Buscher
Journal:  Med Welt       Date:  1974-03-15

9.  Individualized patient assessment in the treatment of epilepsy with sodium valproate.

Authors:  R G Beran; T Read; M Reid; R H Rischbieth; L Sansom; G J Schapel; P E Stanley
Journal:  Epilepsia       Date:  1980-08       Impact factor: 5.864

10.  Valproic acid therapy in childhood epilepsy.

Authors:  D L Coulter; H Wu; R J Allen
Journal:  JAMA       Date:  1980 Aug 22-29       Impact factor: 56.272
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  8 in total

1.  Fatal pancytopenia during high-dose valproate monotherapy.

Authors:  J Rajantie; M Kajosaari; V Ylitalo
Journal:  Eur J Pediatr       Date:  1992-08       Impact factor: 3.183

2.  Perioperative levetiracetam for prevention of seizures in supratentorial brain tumor surgery.

Authors:  Iris Zachenhofer; Markus Donat; Stefan Oberndorfer; Karl Roessler
Journal:  J Neurooncol       Date:  2010-06-06       Impact factor: 4.130

3.  Sodium valproate and neutropenia.

Authors:  D N Symon; G Russell
Journal:  Arch Dis Child       Date:  1983-03       Impact factor: 3.791

4.  Neutropenia and Leukopenia After Cross Taper From Quetiapine to Divalproex for the Treatment of Borderline Personality Disorder.

Authors:  Caroline Richmond; Stephanie Coveart
Journal:  Fed Pract       Date:  2022-04-11

5.  Haematological disturbances during long-term valproate therapy.

Authors:  B Brichard; C Vermylen; J M Scheiff; J Ninane; G Cornu
Journal:  Eur J Pediatr       Date:  1994-05       Impact factor: 3.183

6.  Thrombotic microangiopathy associated with Valproic acid toxicity.

Authors:  Sean A Hebert; Timothy P Bohan; Christian L Erikson; Rita D Swinford
Journal:  BMC Nephrol       Date:  2017-08-03       Impact factor: 2.388

Review 7.  Anesthetic considerations for stereotactic electroencephalography implantation.

Authors:  Chakrabarti Rajkalyan; Anurag Tewari; Shilpa Rao; Rafi Avitsian
Journal:  J Anaesthesiol Clin Pharmacol       Date:  2019 Oct-Dec

8.  Assessment of need for hemostatic evaluation in patients taking valproic acid: A retrospective cross-sectional study.

Authors:  Demi S Post; Arian van der Veer; Olaf E M G Schijns; Sylvia Klinkenberg; Kim Rijkers; G Louis Wagner; Vivianne H J M van Kranen-Mastenbroek; Paul C P H Willems; Paul W M Verhezen; Erik A M Beckers; Floor C J I Heubel-Moenen; Yvonne M C Henskens
Journal:  PLoS One       Date:  2022-02-25       Impact factor: 3.240
  8 in total

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