Literature DB >> 6812475

Recent developments in the diagnosis and therapy of epilepsy.

J Engel, A S Troupin, P H Crandall, M B Sterman, C G Wasterlain.   

Abstract

Recent advances in the diagnosis of epilepsy include the development of a clinically useful classification of epileptic seizures and the recognition of specific epileptic disorders. These advances have been aided by the advent of x-ray computed tomography, long-term electroencephalographic telemetry, and video monitoring. Techniques for functional imaging of the human brain promise even greater diagnostic capabilities. New antiepileptic drugs have improved medical management, and technical and theoretical advances in pharmacokinetics have permitted physicians to design balanced dosing for individual patients. Although currently underused, surgical treatment of partial complex epilepsy can be safe and effective when used appropriately. Operant conditioning of electroencephalography may become another practical alternative therapy. Contributions of basic research to understanding the complications of status epilepticus have influenced treatment protocols and greatly improved the prognosis of this potentially lethal condition.

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Year:  1982        PMID: 6812475     DOI: 10.7326/0003-4819-97-4-584

Source DB:  PubMed          Journal:  Ann Intern Med        ISSN: 0003-4819            Impact factor:   25.391


  4 in total

1.  Evaluation of the pharmacokinetic interaction between diazepam and ACC-9653 (a phenytoin prodrug) in healthy male volunteers.

Authors:  E K Hussey; G E Dukes; J A Messenheimer; K L Brouwer; K H Donn; T F Krol; L J Hak
Journal:  Pharm Res       Date:  1990-11       Impact factor: 4.200

2.  An assessment of MEG coherence imaging in the study of temporal lobe epilepsy.

Authors:  Kost Elisevich; Neetu Shukla; John E Moran; Brien Smith; Lonni Schultz; Karen Mason; Gregory L Barkley; Norman Tepley; Valentina Gumenyuk; Susan M Bowyer
Journal:  Epilepsia       Date:  2011-03-02       Impact factor: 5.864

3.  Epileptic seizure disorders. Developments in diagnosis and therapy.

Authors:  E Niedermeyer; W Froescher; R S Fisher
Journal:  J Neurol       Date:  1985       Impact factor: 4.849

4.  An audit of therapeutic drug monitoring of anticonvulsants.

Authors:  P C Sharpe; J Morrow; E R Trimble
Journal:  Ulster Med J       Date:  1995-10
  4 in total

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