Pulmonary renal syndromes. II. Etiology and pathogenesis.

Numerous systemic diseases share immunopathogenic mechanisms. This article reviews the proposed etiologies and immunopathogenic mechanisms of a group of diseases which share pulmonary and renal abnormalities. Specifically, we discuss the following diseases: Good-pasture's syndrome, systemic lupus erythematosus, progressive systemic sclerosis, Wegener's granulomatosis, lymphomatoid granulomatosis, and Churg-Strauss syndrome.