Studies on the efficacy of a new 20% fat emulsion in pediatric parenteral nutrition.

A new 20% safflower oil emulsion was studied in a small series of pediatric patients. Eight infants and children were evaluated over a 2-week period. The 20% fat emulsion supplied a major portion of daily caloric requirements. No serious side effects or toxicity were noted. No major changes in blood chemistries were observed; however, a statistically significant increase in serum albumin was noted. In addition, 63% of the patients gained weight during the study. This investigation supports the contention that 20% Liposyn is a safe and effective component of a parenteral nutrition program for children.