Literature DB >> 6809079

Human blood monocytes and platelets share a cell surface component.

J J Burckhardt, W H Anderson, J F Kearney, M D Cooper.   

Abstract

We describe a surface determinant shared by human monocytes and cells of the megakaryocytic axis that has been identified using a mouse monoclonal antibody. This monocyte-platelet antigen (MPA) is expressed on all (greater than 99%) of peripheral blood monocytes, platelets, and megakaryocytes. It is also expressed weakly on the monocytic cell line U937 and the promyelocytic line HL60 and is present on cells from 3 of 4 AML patients examined. It is absent from polymorphonuclear leukocytes, T and B lymphocytes, erythrocytes, and a panel of hematopoietic cell lines. MPA is stripped from monocyte membranes with pronase and is reexpressed overnight. The determinant is carried on a noncovalently linked biomolecular complex with molecular weights of 93,000 and 135,000.

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Year:  1982        PMID： 6809079

Source DB:  PubMed          Journal:  Blood        ISSN： 0006-4971            Impact factor:   22.113


  10 in total

1.  Platelet glycoprotein IIb. Chromosomal localization and tissue expression.

Authors:  P F Bray; J P Rosa; G I Johnston; D T Shiu; R G Cook; C Lau; Y W Kan; R P McEver; M A Shuman
Journal:  J Clin Invest       Date:  1987-12       Impact factor: 14.808

2.  Binding of fibrinogen to human monocytes.

Authors:  D C Altieri; P M Mannucci; A M Capitanio
Journal:  J Clin Invest       Date:  1986-10       Impact factor: 14.808

3.  Monocytes and platelets share the glycoproteins IIb and IIIa that are absent from both cells in Glanzmann's thrombasthenia type I.

Authors:  G Gogstad; O Hetland; N O Solum; H Prydz
Journal:  Biochem J       Date:  1983-08-15       Impact factor: 3.857

4.  Aggregation of human peripheral blood mononuclear cells by calcium ionophore A23187. Comparison with the aggregation of platelets and defective response in Glanzmann's thrombasthenia.

Authors:  A M Cerbone; G Di Minno; P Montemurro; C Iride; N Ciavarella; A Scillitani; N Semeraro
Journal:  Agents Actions       Date:  1988-06

5.  Synthesis of analogs of human platelet membrane glycoprotein IIb-IIIa complex by chicken peripheral blood thrombocytes.

Authors:  T J Kunicki; P J Newman
Journal:  Proc Natl Acad Sci U S A       Date:  1985-11       Impact factor: 11.205

6.  Complement receptor type three (CD11b/CD18) of human polymorphonuclear leukocytes recognizes fibrinogen.

Authors:  S D Wright; J I Weitz; A J Huang; S M Levin; S C Silverstein; J D Loike
Journal:  Proc Natl Acad Sci U S A       Date:  1988-10       Impact factor: 11.205

7.  Expression of platelet membrane glycoproteins and alpha-granule proteins by a human erythroleukemia cell line (HEL).

Authors:  A Tabilio; J P Rosa; U Testa; N Kieffer; A T Nurden; M C Del Canizo; J Breton-Gorius; W Vainchenker
Journal:  EMBO J       Date:  1984-02       Impact factor: 11.598

8.  Human megakaryocytes. V. Changes in the phenotypic profile of differentiating megakaryocytes.

Authors:  R B Levene; J M Lamaziere; H E Broxmeyer; L Lu; E M Rabellino
Journal:  J Exp Med       Date:  1985-03-01       Impact factor: 14.307

9.  Absence of platelet membrane glycoproteins IIb/IIIa from monocytes.

Authors:  K J Clemetson; J L McGregor; R P McEver; Y V Jacques; D F Bainton; W Domzig; M Baggiolini
Journal:  J Exp Med       Date:  1985-05-01       Impact factor: 14.307

10.  Human T cell activation. III. Rapid induction of a phosphorylated 28 kD/32 kD disulfide-linked early activation antigen (EA 1) by 12-o-tetradecanoyl phorbol-13-acetate, mitogens, and antigens.

Authors:  T Hara; L K Jung; J M Bjorndahl; S M Fu
Journal:  J Exp Med       Date:  1986-12-01       Impact factor: 14.307
  10 in total

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