Literature DB >> 6809074

Electron microscopic localization of factor-VIII-related antigen in adult human blood vessels.

J H Rand, R E Gordon, I I Sussman, S V Chu, V Solomon.   

Abstract

We have localized factor-VIII-related antigen, using immunofluorescence and electron microscopy, in adult human blood vessels. In addition to its presence in endothelial cells, the antigen was localized within subendothelium and the layers of elastic lamina closest to the lumen. Also, we provide the first morphological evidence that factor-VIII-related antigen is associated with collagen fibrils within the vessel wall. These studies suggest that this subendothelial factor-VIII-related antigen may play a role in the adhesion of platelets to subendothelial components following endothelial injury.

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Year:  1982        PMID： 6809074

Source DB:  PubMed          Journal:  Blood        ISSN： 0006-4971            Impact factor:   22.113


  10 in total

1.  Morphological relationships of von Willebrand factor, type VI collagen, and fibrillin in human vascular subendothelium.

Authors:  X X Wu; R E Gordon; R W Glanville; H J Kuo; R R Uson; J H Rand
Journal:  Am J Pathol       Date:  1996-07       Impact factor: 4.307

2.  Electron-microscopic and immunocytochemical analyses of Weibel-Palade bodies in the human umbilical vein during pregnancy.

Authors:  H Kagawa; S Fujimoto
Journal:  Cell Tissue Res       Date:  1987-09       Impact factor: 5.249

3.  ADP-dependent common receptor mechanism for binding of von Willebrand factor and fibrinogen to human platelets.

Authors:  S Timmons; M Kloczewiak; J Hawiger
Journal:  Proc Natl Acad Sci U S A       Date:  1984-08       Impact factor: 11.205

4.  Von Willebrand protein binds to extracellular matrices independently of collagen.

Authors:  D D Wagner; M Urban-Pickering; V J Marder
Journal:  Proc Natl Acad Sci U S A       Date:  1984-01       Impact factor: 11.205

5.  Immunohistochemical detection of human small lymphatic vessels under normal and pathological conditions using the LYVE-1 antibody.

Authors:  Yuri Akishima; Kinji Ito; Lijun Zhang; Yukio Ishikawa; Hideki Orikasa; Hideko Kiguchi; Yoshikiyo Akasaka; Kazuo Komiyama; Toshiharu Ishii
Journal:  Virchows Arch       Date:  2004-01-14       Impact factor: 4.064

6.  Heterogeneous distribution of Weibel-Palade bodies and von Willebrand factor along the porcine vascular tree.

Authors:  J Gebrane-Younès; L Drouet; J P Caen; L Orcel
Journal:  Am J Pathol       Date:  1991-12       Impact factor: 4.307

7.  Uptake of oleate by isolated rat adipocytes is mediated by a 40-kDa plasma membrane fatty acid binding protein closely related to that in liver and gut.

Authors:  W Schwieterman; D Sorrentino; B J Potter; J Rand; C L Kiang; D Stump; P D Berk
Journal:  Proc Natl Acad Sci U S A       Date:  1988-01       Impact factor: 11.205

8.  Co-localization of von Willebrand factor and type VI collagen in human vascular subendothelium.

Authors:  J H Rand; X X Wu; B J Potter; R R Uson; R E Gordon
Journal:  Am J Pathol       Date:  1993-03       Impact factor: 4.307

9.  Divergent fates of von Willebrand factor and its propolypeptide (von Willebrand antigen II) after secretion from endothelial cells.

Authors:  D D Wagner; P J Fay; L A Sporn; S Sinha; S O Lawrence; V J Marder
Journal:  Proc Natl Acad Sci U S A       Date:  1987-04       Impact factor: 11.205

10.  Constitutive phosphorylation of the mTORC2/Akt/4E-BP1 pathway in newly derived canine hemangiosarcoma cell lines.

Authors:  Atsuko Murai; Samah Abou Asa; Atsushi Kodama; Akihiro Hirata; Tokuma Yanai; Hiroki Sakai
Journal:  BMC Vet Res       Date:  2012-07-29       Impact factor: 2.741
  10 in total

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